4056-78-4

Basic information

• Product Name: NORCAMPHORICACID
• Synonyms: NORCAMPHORICACID;1,3-Cyclopentanedicarboxylic acid;Cyclopentane-1,3-dicarboxylic acid
• CAS NO: 4056-78-4
• Molecular Formula: C₇H₁₀O₄
• Molecular Weight: 158.15
• Mol File: 4056-78-4.mol
• Article Data: 10

Chemical Properties

• Melting Point: 121.5 °C
• Boiling Point: 320.7°Cat760mmHg
• Flash Point: 161.9°C
• Appearance: /
• Density: 1.396g/cm³
• Vapor Pressure: 6.51E-05mmHg at 25°C
• Refractive Index: 1.535
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.23±0.40(Predicted)
• CAS DataBase Reference: NORCAMPHORICACID(CAS DataBase Reference)
• NIST Chemistry Reference: NORCAMPHORICACID(4056-78-4)
• EPA Substance Registry System: NORCAMPHORICACID(4056-78-4)

Safety Data

• Hazardous Substances Data: 4056-78-4(Hazardous Substances Data)

Usage

Description

NORCAMPHORICACID, also known as Cyclopentane-1,3-dicarboxylic Acid, is an organic compound with a unique structure that features a cyclopentane ring and two carboxylic acid groups. It is known for its potential applications in various fields due to its chemical properties.

Uses

Used in Chemical Research:
NORCAMPHORICACID is used as a research compound for the study of ruthenium-catalyzed oxidation of alkenes and monoenic fatty acids. This application is significant as it contributes to the understanding of chemical reactions and the development of new synthetic methods in the field of organic chemistry.
Used in Pharmaceutical Industry:
NORCAMPHORICACID can be utilized as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Material Science:
Due to its chemical properties, NORCAMPHORICACID may also find applications in the development of new materials with specific properties, such as polymers with tailored characteristics for use in various industries, including automotive, aerospace, and electronics.

InChI:InChI=1/C7H10O4/c8-6(9)4-1-2-5(3-4)7(10)11/h4-5H,1-3H2,(H,8,9)(H,10,11)/t4-,5+

Upstream product

• 498-66-8 norborn-2-ene 
• 87238-75-3 tricyclo<5.2.1.0².⁶>dec-2(6)-ene 
• 71720-43-9 (Bicyclo<2.2.1>hept-2-en-2-yl)-1-ethanon 
• 497-38-1 Norbornan-2-on 
• 18084-03-2 2-ethynylbicyclo[2.2.1]heptan-2-ol 

Downstream Products

• 2435-36-1 cyclopentane?1,3?dimethyl formate 
• 2453-00-1 1,3-dimethylcyclopentane 
• 905457-34-3 4-iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)bicyclo[2.2.1]heptane-1-carboxamide 
• 1299426-10-0 4-iodo-N-(2-(4-(2-hydroxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)bicyclo[2.2.1]heptane-1-carboxamide 
• 15448-76-7 dimethyl bicyclo<2.2.1>heptane-1,4-dicarboxylate 
• 15448-77-8 4-carbomethoxybicyclo<2.2.1>heptane-1-carboxylic acid 
• 1252672-36-8 4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid 
• 737693-57-1 4-aminobicyclo[2.2.1]heptane-1-carboxylic acid 
• 1403865-38-2 benzyl 4-hydroxybicyclo[2.2.1]heptan-1-ylcarbamate 
• 1610729-44-6 (S,S)-dibenzyl cyclopentyl 1,3-dicarboxylate 
• 36010-89-6 (S,S)-cyclopentyl 1,3-dicarboxylic acid 
• 15544-51-1 bicyclo<2.2.1>heptane-1,4-dicarboxylic acid 
• 62959-20-0 1,3-cyclopentanedicarboxamide 
• 1252672-35-7 4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester 

Relevant articles and documents

-

-

SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R1, R2, R3, and R4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.

Design, synthesis, radiolabeling, and in vitro and in vivo evaluation of bridgehead iodinated analogues of N -{2-[4-(2-methoxyphenyl)piperazin-1-yl] ethyl}- N -(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) as potential SPECT ligands for the 5-HT1A receptor

Here we describe the design, synthesis, and pharmacological profile of 5-HT1A receptor ligands related to 1 (WAY-100635). The cyclohexyl moiety in 1 and its O-desmethylated analogue 3 were replaced by the bridgehead iodinated bridge-fused rings: adamantyl, cubyl, bicyclo[2.2.2]octyl, or bicyclo[2.2.1]heptyl. All analogues displayed a (sub)nanomolar affinity for the 5-HT1A receptor in vitro. Compounds 6b and 7b appeared to be selective for this receptor over other relevant receptors and could easily be iodinated with radioactive iodine-123. In humane hepatocytes, [ 123I]6b showed a low propensity for amide hydrolysis and a stable carbon-iodine bond. The biodistribution of [123I]6b and [ 123I]7b in rats revealed that the carbon-iodine bond was also stable in vivo. Unfortunately, the brain uptake and the specificity for both radioligands were significantly lower than those of the parent molecule 1. In conclusion, the designed tracers are not suitable for SPECT imaging.