40571-19-5

Basic information

• Product Name: 1-phenyl-2-adamantanone
• Synonyms: 1-phenyl-2-adamantanone
• CAS NO: 40571-19-5
• Molecular Weight: 226.318
• Mol File: 40571-19-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-phenyl-2-adamantanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-2-adamantanone(40571-19-5)
• EPA Substance Registry System: 1-phenyl-2-adamantanone(40571-19-5)

Safety Data

• Hazardous Substances Data: 40571-19-5(Hazardous Substances Data)

Upstream product

• 27567-85-7 4-Protoadamantanone 
• 40600-19-9 1-Phenyl-2-adamantyl-formiat 
• 61848-80-4 4-phenyltricyclo[4.3.1.0^3,8]decan-4-ol 
• 27567-85-7 4-protoadamantanone 
• 40571-15-1 1-phenyl-2-adamantanol 

Downstream Products

• 117077-12-0 2-(cyanomethyl)-1-phenyladamantane 
• 117077-16-4 1-Phenyl-adamantane-2-carboxylic acid amide 
• 117077-17-5 2-(1-Phenyl-adamantan-2-yl)-acetamide 
• 117077-35-7 Thiophosphoric acid S-[N-(1-phenyl-adamantan-2-ylmethyl)-carbamimidoylmethyl] ester 
• 117077-21-1 C-(1-Phenyl-adamantan-2-yl)-methylamine; hydrochloride 
• 117077-58-4 2-(1-Phenyl-adamantan-2-yl)-ethylamine; hydrochloride 
• 117077-26-6 2-Chloro-N-(1-phenyl-adamantan-2-ylmethyl)-acetamidine; hydrochloride 
• 117118-91-9 N-<2-(1-phenyl-2-adamantyl)ethyl>-2-mercaptoacetamidinium hydrochloride 
• 117077-28-8 2-Chloro-N-[2-(1-phenyl-adamantan-2-yl)-ethyl]-acetamidine; hydrochloride 
• 117077-38-0 N-[2-(1-Phenyl-adamantan-2-yl)-ethyl]-2-{N-[2-(1-phenyl-adamantan-2-yl)-ethyl]-carbamimidoylmethyldisulfanyl}-acetamidine; hydrochloride 
• 856322-62-8 1-phenyltricyclo[3.3.1.1^3,7]decan-2-carboxylic acid 
• 1257380-64-5 1-phenyl-tricyclo[3.3.1.1(3,7)]decan-2-amine 
• 1014694-35-9 C₁₆H₁₉NO 
• 1609113-65-6 C₁₇H₂₀O 

Relevant articles and documents

Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines

Adamantanamines 16, 18, 21, 24, 27, 28, 30, 32, 35, 36, 37, 40, 46 and 48 were synthesized and tested for anti-influenza A virus and trypanocidal activity. The stereoelectronic requirements for optimal antiviral and trypanocidal potency were investigated.

trans-2,2′-Bi(1-phenyladamantylidene): The most twisted biadamantylidene

The Grignard coupling of 2,2-dibromo-1-phenyladamantane gave trans-2,2′-bi(1-phenyladamantylidene) (1-Ph). Single-crystal X-ray analysis indicated that 1-Ph has a 23.2° twisted double bond, which is much more distorted than that of parent 2,2′-biadamantylidene (1-H) and that of the ethyl-substituted derivative (1-Et). A cyclic voltammogram showed a reversible electron oxidation wave at 0.87 V vs Fc/Fc+, which is 0.19 V lower than 1-H, indicating a significant increase in the HOMO energy level due to the distortion. The reaction of 1-Ph with 0.9 equiv of bromine gave an intramolecular Friedel-Crafts alkylation product, while bromination of 1-H and 1-Me has been reported to give a bridged bromonium ion and a rearranged product, 2-(1-methyl-2-adamantylidene)-4-bromotricyclo [5,3,1,03.9]undec-4-ene, respectively.