40575-41-5

Basic information

• Product Name: 2-METHYL-4-OCTANOL
• Synonyms: 2-METHYL-4-OCTANOL;2-METHYL-4-OCTANOL 99%;2-Methyloctan-4-ol
• CAS NO: 40575-41-5
• Molecular Formula: C₉H₂₀O
• Molecular Weight: 144.25
• Mol File: 40575-41-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 6.15°C (estimate)
• Boiling Point: 192.9°C (estimate)
• Flash Point: 76.3°C
• Appearance: /
• Density: 0.8150
• Vapor Pressure: 0.158mmHg at 25°C
• Refractive Index: 1.4260
• CAS DataBase Reference: 2-METHYL-4-OCTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-4-OCTANOL(40575-41-5)
• EPA Substance Registry System: 2-METHYL-4-OCTANOL(40575-41-5)

Safety Data

• Hazardous Substances Data: 40575-41-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H20O/c1-4-5-6-9(10)7-8(2)3/h8-10H,4-7H2,1-3H3

Upstream product

• 110-62-3 pentanal 
• 926-62-5 isobutylmagnesium bromide 
• 7492-38-8 2-methyloctan-4-one 
• 693-03-8 n-butyl magnesium bromide 
• 590-86-3 isovaleraldehyde 
• 109-65-9 1-bromo-butane 
• 598-23-2 3-methyl-but-1-yne 
• 566189-63-7 7-methyl-5-(triethylsilyl)oxy-3-octyne 
• 693-04-9 butyl magnesium bromide 

Downstream Products

• 7492-38-8 2-methyloctan-4-one 
• 128126-01-2 (3,5-Dinitro-phenyl)-carbamic acid (R)-1-isobutyl-pentyl ester 
• 128126-01-2 (3,5-Dinitro-phenyl)-carbamic acid (S)-1-isobutyl-pentyl ester 

Relevant articles and documents

Ligand-controlled, tunable silver-catalyzed C-H amination

The development of readily tunable and regioselective C-H functionalization reactions that operate solely through catalyst control remains a challenge in modern organic synthesis. Herein, we report that simple silver catalysts supported by common nitrogenated ligands can be used to tune a nitrene transfer reaction between two different types of C-H bonds. The results reported herein represent the first example of ligand-controlled and site-selective silver-promoted C-H amination.

Solvent-modulated Pd/C-catalyzed deprotection of silyl ethers and chemoselective hydrogenation

Recently we have reported undesirable and frequent deprotection of the TBDMS protective group of a variety of hydroxyl functions occurred under neutral and mild hydrogenation conditions using 10% Pd/C in MeOH. The deprotection of silyl ethers is susceptible to significant solvent effect. TBDMS and TES protecting groups were selectively cleaved in the presence of acid-sensitive functional groups such as TIPS ether, TBDPS ether and dimethyl acetal under hydrogenation condition using 10% Pd/C in MeOH. In contrast, chemoselective hydrogenation of reducible functional groups such as acetylene, olefin and benzyl ether, proceeds in the presence of TBDMS or TES ethers in AcOEt or MeCN.

Aggregation pheromones and host kairomones of West Indian sugarcane weevil, Metamasius hemipterus sericeus

Coupled gas chromatographic-electroantennographic detection (GC-EAD) analyses and coupled GC-mass spectrometry (MS) of volatiles produced by male and female West Indian sugarcane weevils (WISW), Metamasius hemipterus sericeus (Oliv.), revealed eight male specific, EAD-active compounds: 3-pentanol (1), 2-methyl-4-heptanol (2), 2-methyl-4-octanol (3) 4-methyl-5-nonanol (4), and the corresponding ketones. In field experiments in Florida, alcohols 1-4 in combination with sugarcane were most attractive, whereas addition of the ketones or replacement of alcohols with ketones significantly reduced attraction. In Costa Rica field experiments testing alcohols 1-4 singly and in all binary, ternary, and quaternary combinations revealed 4 in combination with 2 was the major aggregation pheromone, equally attracting male and female WISW. Stereoisomeric 4 and (4S,5S)-4, the only isomer produced by WISW, were equally attractive. Addition of 4S-, 4R- or (±)-2 to (4S,5S)-4 significantly enhanced attraction Sugarcane stalks in combination with 2 plus 4 (ratio of 1:8) were highly synergistic, whereas EAD-active sugarcane volatiles ethyl acetate, ethyl propionate, or ethyl butyrate only moderately increased attractiveness of the pheromone lure.