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40594-87-4

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40594-87-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 40594-87-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,5,9 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 40594-87:
(7*4)+(6*0)+(5*5)+(4*9)+(3*4)+(2*8)+(1*7)=124
124 % 10 = 4
So 40594-87-4 is a valid CAS Registry Number.

40594-87-4Relevant articles and documents

Biarylhydrazine compounds and their adducts and applications in the preparation of antitumor drugs

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Paragraph 0058; 0064; 0065; 0103-0107, (2022/03/27)

The present invention discloses a biarylhydrazine compound and its application in the preparation of antitumor drugs, the structure of the arylhydrazine compound as shown in formula I, the adduct is a biarylhydrazine compound on the hydrazine group plus benzyloxycarbonyl glycyl prolyl. The anticancer activity of the biarylhydrazine compounds of the present invention is superior to that of the existing positive control drug procarbazine; its Z-GP adduct can significantly reduce in vitro toxicity and in vivo toxicity to normal cells, and can be excised by FΑP-α enzyme specific hydrolysis in vivo (Z-GP) to release hydrolysate products; its Z-GP adduct can significantly inhibit tumor growth in tumor-bearing nude mice and reduce toxicity to non-target organs.

An efficient transition-metal-free synthesis of 1H-indazoles from arylhydrazones with montmorillonite K-10 under O2 atmosphere

Yu, Jin,Lim, Jin Woo,Kim, Su Yeon,Kim, Jimin,Kim, Jae Nyoung

supporting information, p. 1432 - 1436 (2015/03/04)

An efficient transition-metal-free synthetic method of 1H-indazoles has been developed. The reaction of arylhydrazones in the presence of montmorillonite K-10 in 1,2-dichlorobenzene at 130 °C afforded 1H-indazoles in good yields most likely via a sequenti

Mild method for the synthesis of 1H-indazoles through oxime-phosphonium ion intermediate

Paul, Saurav,Panda, Subhankar,Manna, Debasis

, p. 2480 - 2483 (2014/05/06)

The synthesis of 1H-indazoles from o-aminobenzoximes is achieved via N-N bond formation using triphenylphosphine, I2, and imidazole. Selective formation of oxime-phosphonium ion intermediate in the presence of the amino group is the driving for

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