406954-88-9

Basic information

• Product Name: N-(2,2-dimethoxyethyl)-N-(2-oxo-2-(2-(2-bromophenyl)ethylamino)ethyl)cyclohexanecarboxamide
• Synonyms: N-(2,2-dimethoxyethyl)-N-(2-oxo-2-(2-(2-bromophenyl)ethylamino)ethyl)cyclohexanecarboxamide
• CAS NO: 406954-88-9
• Molecular Weight: 455.392
• Mol File: 406954-88-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2,2-dimethoxyethyl)-N-(2-oxo-2-(2-(2-bromophenyl)ethylamino)ethyl)cyclohexanecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,2-dimethoxyethyl)-N-(2-oxo-2-(2-(2-bromophenyl)ethylamino)ethyl)cyclohexanecarboxamide(406954-88-9)
• EPA Substance Registry System: N-(2,2-dimethoxyethyl)-N-(2-oxo-2-(2-(2-bromophenyl)ethylamino)ethyl)cyclohexanecarboxamide(406954-88-9)

Safety Data

• Hazardous Substances Data: 406954-88-9(Hazardous Substances Data)

Upstream product

• 65185-58-2 2-(2-bromophenyl)ethanamine 
• 444815-17-2 N-[2-(2-bromophenyl)ethyl]formamide 
• 50-00-0 formaldehyd 
• 22483-09-6 2,2-dimethoxyethylamine 
• 98-89-5 Cyclohexanecarboxylic acid 
• 406954-87-8 phenylmethyl 2-[N-(2,2-dimethoxyethyl)cyclohexylcarbonylamino]acetate 
• 98265-88-4 phenylmethyl 2-[(2,2-dimethoxyethyl)amino]acetate 
• 60744-45-8 2-[N-(2,2-dimethoxyethyl)cyclohexylcarbonylamino]acetic acid 

Downstream Products

• 59343-45-2 8-bromopraziquantel 
• 55268-74-1 2-cyclohexanecarbonyl-1,2,3,6,7,11b-hexahydro-pyrazino[2,1-a]isoquinolin-4-one 
• 406954-89-0 1-[2-(2-bromophenyl)ethyl]-4-(cyclohexylcarbonyl)-1,3,4-trihydropyrazin-2-one 

Relevant articles and documents

Praziquantel derivatives with antischistosomal activity: Aromatic ring modification

A series of aromatic ring-modified praziquantel derivatives were prepared and evaluated against juvenile and adult stage of Schistosoma japonicumin. Several analogs comparable in activity to the drug praziquantel have been identified based on in vitro and in vivo japonuicum schistosomes worm viability assay. Structure and activity relationship of these praziquantel aromatic ring-modified compounds was revealed. Specifically, a compound in which a bromine has been introduced in the aromatic ring of praziquantel demonstrated close antischistosomal activity to praziquantel in vivo.