40696-22-8

Basic information

• Product Name: 2-METHOXY-1-NAPHTHALENEMETHANOL
• Synonyms: (2-METHOXY-1-NAPHTHYL)METHANOL;2-METHOXY-1-NAPHTHALENEMETHANOL;RARECHEM AL BD 0091;1-(Hydroxymethyl)-2-methoxynaphthalene;2-Methoxy-1-naphthalenemethanol,98%;(2-Methoxynaphth-1-yl)methanol;(2-methoxynaphthalen-1-yl)methanol
• CAS NO: 40696-22-8
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.22
• Mol File: 40696-22-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 100-104 °C
• Boiling Point: 283.23°C (rough estimate)
• Flash Point: 163.1°C
• Appearance: /
• Density: 1.0750 (rough estimate)
• Vapor Pressure: 2.06E-05mmHg at 25°C
• Refractive Index: 1.6010 (estimate)
• CAS DataBase Reference: 2-METHOXY-1-NAPHTHALENEMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-1-NAPHTHALENEMETHANOL(40696-22-8)
• EPA Substance Registry System: 2-METHOXY-1-NAPHTHALENEMETHANOL(40696-22-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 40696-22-8(Hazardous Substances Data)

Usage

Chemical Properties

white to beige crystalline powder or

InChI:InChI=1/C12H12O2/c1-14-12-7-6-9-4-2-3-5-10(9)11(12)8-13/h2-7,13H,8H2,1H3

Upstream product

• 67367-39-9 1-chloromethyl-2-methoxynaphthalene 
• 136402-93-2 1-aminomethyl-2-methoxynaphthalene 
• 5392-12-1 2-methoxy-1-naphthaldehyde 
• 64-19-7 acetic acid 
• 93-04-9 2-Methoxynaphthalene 

Downstream Products

• 67367-39-9 1-chloromethyl-2-methoxynaphthalene 
• 862806-04-0 1-(3,5-bis-benzyloxy-benzyloxymethyl)-2-methoxy-naphthalene 
• 862806-05-1 2-methoxy-1-(3,4,5-tris-benzyloxy-benzyloxymethyl)-naphthalene 
• 34225-11-1 3-(2-methoxynaphthalen-1-yl)propanoic acid 
• 562838-44-2 3-[Bis(4-fluorophenyl)methyl]-1-[(2-methoxy-1-naphthyl)methyl]-4-piperidinone 
• 1032464-79-1 C₆₁H₅₄O₈ 
• 5392-12-1 2-methoxy-1-naphthaldehyde 
• 1082692-61-2 3-(2-methoxynaphthalen-1-yl)acrylic acid 

Relevant articles and documents

Base-Induced Cyclisation of ortho -Substituted 2-Phenyloxazolines to Give 3-Aminobenzofurans and Related Heterocycles

Treatment of ortho -benzyloxyphenyloxazolines with butyllithium and potassium tert -butoxide results in cyclisation with ring opening of the oxazoline to give 2-aryl-3-aminobenzofurans. The reaction also occurs with the corresponding benzylthio and benzylamino compounds to give benzothiophenes and indoles, respectively. Use of an ortho -allyloxyphenyloxazoline gives the corresponding 2-vinylbenzofuran, while both α-methylbenzyloxy and benzylsulfonyl compounds form stable spirooxazolidine products. The X-ray structure of an aminobenzothiophene product has been determined.

Palladium-catalyzed amination of chloromethylnaphthalene and chloromethylanthracene derivatives with various amines

Palladium-catalyzed amination of chloromethylnaphthalene and chloromethylanthracene derivatives to produce naphthylamines and anthrylamines in satisfactory to good yields has been developed. The unprecedented amination reactions proceeded smoothly under mild conditions in the presence of Pd(PPh3)4 as a catalyst.