40700-40-1

Basic information

• Product Name: Ethyl 4-(dimethylamino)-3-nitrobenzoate
• Synonyms: Ethyl 4-(dimethylamino)-3-nitrobenzoate
• CAS NO: 40700-40-1
• Molecular Formula: C₁₁H₁₄N₂O₄
• Molecular Weight: 238.23986
• Mol File: 40700-40-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl 4-(dimethylamino)-3-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4-(dimethylamino)-3-nitrobenzoate(40700-40-1)
• EPA Substance Registry System: Ethyl 4-(dimethylamino)-3-nitrobenzoate(40700-40-1)

Safety Data

• Hazardous Substances Data: 40700-40-1(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 28096-56-2 4-(N,N-dimethylamino)-3-nitrobenzoic acid 
• 19005-63-1 4-(dimethylamino)-3-nitrobenzonitrile 
• 59935-39-6 4-dimethylamino-3-nitrobenzaldehyde 
• 10287-53-3 ethyl p-dimethyaminolbenzoate 

Relevant articles and documents

Benzene derivatives and pharmaceutical composition

A benzene derivative of the formula (I): STR1 wherein R 1 is hydrogen, C 1-6 -alkyl, C 1-6 -haloalkyl, --NH 2, --NHR 21 ; R 2 is hydroxyl, --OR 22, three- to seven-membered saturated cycloaliphatic amino optionally interrupted by one or more nitrogen, oxygen or sulfur atoms, --NHR 23, --N(R 24) 2, --NH 2 ; R 4 is hydrogen, C 1-6 -alkyl, or --C( O)R 25 ; R 7 is --CO--, --SO 2 --; R 8 is --CO--, single bond; R 12 is --R 11 --R 5 ; R 11 is --N(R 5)--, --NH--, --O--, --N(R 26)--, --N(C( O)R 27)--, --N(C( O)NH 2)--, --N(C( O)NHR 28)--; R 13 is hydrogen, C 1-6 -alkyl, C 1-6 -haloalkyl, --NHC( O)(CH 2) m C 6 H 5, --NHC( O)R 29, --NHC( O)CH(C 6 H 5) 2, --NH 2, --NHR 30, --(CH 2) n C 6 H 5 ; Z is C, CH, N; A is CH, N; R 5 is hydrogen, --CH 2 C 6 H 4 COOH, --CH 2 C 6 H 4 COOR 31, --CH 2 C 6 H 4 OH, --CH 2 C 6 H 4 OR 32, --CH 2 C 6 H 4 NH 2, --CH 2 C 6 H 4 N(R 33) 2, --CH 2 C 6 H 4 -azole, --CH 2 C 6 H 4 NHR 34, --CH 2 C 6 H 4 C 6 H 4 R 14 ; R 14 is azole, --COOH; R 21 to R 34 are independently C 1-6 -alkyl or C 1-6 -haloalkyl; m is 0 to 6; n is 0 to 6; t is 0 or 1, with the proviso that when Z is N, R 5 is hydrogen, --CH 2 C 6 H 4 COOH, --CH 2 C 6 H 4 COOR 31, --CH 2 C 6 H 4 OH, --CH 2 C 6 H 4 OR 32, --CH 2 C 6 H 4 NH 2, --CH 2 C 6 H 4 N(R 33) 2, --CH 2 C 6 H 4 -azole, or --CH 2 C 6 H 4 NHR 34, or a salt thereof, and a pharmaceutical composition comprising said benzene derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier are disclosed.