40711-33-9

Basic information

• Product Name: ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate
• Synonyms: ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate;2,5-Hihydro-5-oxo-1H-pyrazole-3-carboxylic acid ethyl ester
• CAS NO: 40711-33-9
• Molecular Formula: C₆H₈N₂O₃
• Molecular Weight: 156.13932
• Mol File: 40711-33-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Density: 1.272±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 7.78±0.70(Predicted)
• CAS DataBase Reference: ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate(40711-33-9)
• EPA Substance Registry System: ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate(40711-33-9)

Safety Data

• Hazardous Substances Data: 40711-33-9(Hazardous Substances Data)

Usage

General Description

Ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate is a chemical compound with the molecular formula C7H10N2O3. It is a derivative of pyrazole, a heterocyclic organic compound. ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate is used in the synthesis of pharmaceuticals and agrochemicals due to its potential pharmacological and biological activities. Ethyl 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate has been studied for its anticonvulsant and analgesic properties, suggesting it may have potential as a therapeutic agent for various medical conditions. Additionally, it is also used as an intermediate in the production of other organic compounds. However, its exact applications and uses may vary based on its specific properties and synthesis methods.

Upstream product

• 37832-55-6 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid 
• 10302-94-0 (Z)-2-chloro-2-butenedioic acid, diethyl ester 
• 762-21-0 acetylenedicarboxylic acid diethyl ester 
• 64-17-5 ethanol 
• 563-41-7 semicarbazide hydrochloride 
• 127-09-3 sodium acetate 
• 108-56-5 diethyl oxaloacetate 
• 302-01-2 hydrazine 
• 3702-98-5 ethyl 4,4,4-trichloroacetoacetate 
• 25117-86-6 diazo-succinic acid diethyl ester 

Downstream Products

• 37832-55-6 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid 
• 66483-27-0 5‐oxo‐2,5‐dihydro‐1H‐pyrazole‐3‐carbohydrazide 
• 628331-20-4 3-benzyloxy-1H-pyrazole-5-carboxylic acid methyl ester 
• 52867-49-9 1-benzyl-3-hydroxy-5-methoxycarbonyl-1H-pyrazole 
• 1192313-22-6 ethyl 1-[2-(3-chlorophenyl)-2-oxoethyl]-3-[(3-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}propyl)oxy]-1H-pyrazole-5-carboxylate 
• 1192313-58-8 ethyl 3-[(3-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}propyl)oxy]-1-{2-[4-fluoro-3-(trifluoromethyl)phenyl]-2-oxoethyl}-1-H-pyrazole-5-carboxylate 
• 1192313-86-2 1,1-dimethylethyl 4-[(5-[(ethyloxy)carbonyl]-1-{2-[4-fluoro-3-(trifluoromethyl)phenyl]-2-oxoethyl}-1H-pyrazol-3-yl)oxy]-1-piperidinecarboxylate 
• 1192313-30-6 ethyl 1-(2-oxo-2-m-tolylethyl)-3-(3-(piperidin-1-yl)propoxy)-1H-pyrazole-5-carboxylate 

Relevant articles and documents

THIENO[2,3-C]PYRANS AS CFTR MODULATORS

The present invention discloses compounds according to Formula I: Wherein R is as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment cystic fibrosis by administering a compound of the invention.

A novel method for the synthesis of 3,4-disubstitutedpyrrole-2,5- dicarboxylates from hydrazones derived from α-diazo esters

Hydrazones obtained from α-diazo esters were converted to pyrroles when heated with thionyl chloride in alcohol. Among hydrazones, those substituted with a benzene ring on the β-carbon to the ester are likely to give pyrroles in good yields.

PYRAZOLO [1,5-A]PYRAZINE DERIVATIVE AS ANTAGONISTS OF V1B RECEPTORS

The present invention relates to novel compounds of formula (I) or salts thereof: wherein R is -X-[CH2]n CR4R5 -Y; or a group G; G is one of the groups selected from the list consisting of G1, G2, G3, G4, G5, G6, G7, G8, G9, G10, G11 and G12, and the rest