40749-31-3 Usage
Description
2-Benzofuranglyoxylaldehyde is a chemical compound characterized by the molecular formula C11H6O3. It presents as a white to yellow solid with a melting point in the range of 58-60°C. 2-Benzofuranglyoxylaldehyde is recognized for its utility in organic synthesis, particularly as a key intermediate in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. Its chemical properties render it a versatile building block for synthesizing a broad spectrum of complex organic compounds. However, due to its potential to irritate the skin, eyes, and respiratory system, it requires careful handling.
Uses
Used in Pharmaceutical Industry:
2-Benzofuranglyoxylaldehyde serves as a crucial intermediate in the synthesis of various pharmaceuticals. Its role in this industry is pivotal for creating a range of medicinal compounds, contributing to the development of new treatments and therapies.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Benzofuranglyoxylaldehyde is utilized as an intermediate for the preparation of different agrochemicals. Its application aids in the production of substances that are essential for agricultural advancements and crop protection.
Used in Fine Chemicals Industry:
2-Benzofuranglyoxylaldehyde also finds application in the fine chemicals industry, where it is employed as an intermediate for synthesizing specialty chemicals. These fine chemicals are used in various applications, including fragrances, dyes, and other high-value chemical products.
Used in Materials Science:
2-Benzofuranglyoxylaldehyde holds potential in the field of materials science, particularly for the development of new functional materials. Its unique properties allow it to contribute to the creation of innovative materials with specific functions and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 40749-31-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,7,4 and 9 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 40749-31:
(7*4)+(6*0)+(5*7)+(4*4)+(3*9)+(2*3)+(1*1)=113
113 % 10 = 3
So 40749-31-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H6O3/c11-6-8(12)10-5-7-3-1-2-4-9(7)13-10/h1-6H
40749-31-3Relevant articles and documents
One-pot three-component reactions of methyl ketones, phenols and a nucleophile: An expedient way to synthesize densely substituted benzofurans
Cheng, Cheng,Liu, Changhui,Gu, Yanlong
, p. 8009 - 8017 (2015/12/31)
Three-component reactions of phenylglyoxal monohydrate, phenols, and indoles were developed with the aid of acid-catalyst, which produced various densely substituted benzofurans with good to excellent yields. On the basis of this observation, a one-pot, step-wise reaction was developed by using methyl ketones instead of using phenylglyoxal component in I2/DMSO system. At last, three-component reaction offered a useful way to synthesize densely substituted benzofurans starting from simple and easily available substrates. The indole component can be replaced by some other nucleophiles, such as 1,2,4-trimethoxybenzene and thiophenol.
Design and synthesis of 2-acylbenzothiazoles via in situ cross-trapping strategy from benzothiazoles with aryl ketones
Gao, Qinghe,Wu, Xia,Jia, Fengcheng,Liu, Meicai,Zhu, Yanping,Cai, Qun,Wu, Anxin
, p. 2792 - 2797 (2013/04/24)
An I2/KOH synergistically promoted direct ring-opening aroylation of benzothiazoles with aryl ketones has been discovered. Aryl ketones were seen to act as carbonyl sources to construct 2-acylbenzothiazoles. This reaction could provide an example for the convergent integration of self-labor domino sequences based on an in situ cross-trapping strategy.
Secondary amines and their use in pharmaceutical compositions
-
, (2008/06/13)
Compounds of formula (III): STR1 and esters, amides and pharmaceutically acceptable salts thereof, wherein A1 is hydrogen or methyl; A2 is hydrogen or methyl; n is 1, 2 or 3; and R is hydrogen, chlorine, bromine, hydroxy, nitro, amin
