40755-14-4

Basic information

• Product Name: heptan-4-aminium chloride
• CAS NO: 40755-14-4
• Molecular Formula: C₇H₁₈ClN
• Molecular Weight: 151.6775
• Mol File: 40755-14-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 139.5°C at 760 mmHg
• Flash Point: 41.3°C
• Vapor Pressure: 6.41mmHg at 25°C
• CAS DataBase Reference: heptan-4-aminium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: heptan-4-aminium chloride(40755-14-4)
• EPA Substance Registry System: heptan-4-aminium chloride(40755-14-4)

Safety Data

• Hazardous Substances Data: 40755-14-4(Hazardous Substances Data)

Upstream product

• 57041-04-0 (2-propyl-aziridin-1-yl)-phosphonic acid diethyl ester 

Relevant articles and documents

Synthesis of primary sec-alkylamines via nucleophilic ring-opening of N-phosphorylated aziridines

The novel ring-opening reaction of various 2-alkyl- and 2,2-dimethyl-N-(diethoxyphosphoryl)aziridines (1) and (10) with copper-modified Grignard reagents proceeds regiospecifically at the less hindered carbon. The diethyl N-sec-alkylphosphoramidates (2) thus obtained may efficiently be converted to primary sec-alkylamine hydrochlorides (3) by refluxing with 20% hydrochloric acid. 2,3-Disubstituted N-phosphorylated aziridines except N-phosphorylated cyclohexenimine (4) do not react under the described conditions. Copper-mediated reaction of 2-phenyl-N-(diethoxyphosphoryl)aziridine (7) with Grignard reagents affords a mixture of regioisomers (8) and (9) but still with the preference of ring-opening at the carbon of lesser substitution.