40815-75-6

Basic information

• Product Name: 5'-ALLYLOXY-2'-HYDROXYACETOPHENONE
• Synonyms: 5'-ALLYLOXY-2'-HYDROXYACETOPHENONE;1-(5-(allyloxy)-2-hydroxyphenyl)ethanone
• CAS NO: 40815-75-6
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21118
• Mol File: 40815-75-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5'-ALLYLOXY-2'-HYDROXYACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-ALLYLOXY-2'-HYDROXYACETOPHENONE(40815-75-6)
• EPA Substance Registry System: 5'-ALLYLOXY-2'-HYDROXYACETOPHENONE(40815-75-6)

Safety Data

• Hazardous Substances Data: 40815-75-6(Hazardous Substances Data)

Usage

Preparation

Preparation by reaction of allyl bromide on quinacetophenone with potassium carbonate in refluxing acetone (86%) or in refluxing methyl ethyl ketone (52%).

Upstream product

• 106-95-6 allyl bromide 
• 490-78-8 2,5-Dihydroxyacetophenone 

Downstream Products

• 90554-75-9 3-Hydroxy-1-<5-(allyloxy)-2-hydroxyphenyl>hexa-2,4-dien-1-one 
• 90554-76-0 (E)-But-2-enoic acid 2-acetyl-4-allyloxy-phenyl ester 
• 110295-19-7 (2Z,4E)-1-(5-Allyloxy-2-hydroxy-phenyl)-3-hydroxy-6-methyl-hepta-2,4,6-trien-1-one 
• 40815-79-0 2-acetyl-3-prop-2'-enyl-1,4-hydroquinone 
• 490-78-8 2,5-Dihydroxyacetophenone 
• 777079-73-9 1-(5-allyloxy-2-methoxyphenyl)-1-ethanone 
• 777079-75-1 1-(2,4-diallyl-3,6-dimethoxyphenyl)-1-ethanone 
• 777079-71-7 1-(2,4-diallyl-3,6-dimethoxyphenyl)-1-ethanol 

Relevant articles and documents

Synthesis and biological evaluation of 3-styrylchromone derivatives as free radical scavengers and α-glucosidase inhibitors

A series of 3-styrylchromone derivatives (4-20) were synthesized and the structure-activity relationships for α-glucosidase inhibition and antioxidant activities were analyzed. Among the synthesized compounds, compounds 15 and 20, which contain a catechol moiety, showed both potent 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity (15: EC50 =17 μM; 20: EC50 =23 μM) and α-glucosidase inhibitory activity (15: IC50 =16 μM; 20: IC50 =10 μM). Our data suggest that 3-styrylchromone derivatives are novel α-glucosidase inhibitors that have the potential to counteract diet-induced hyperglycemia in diabetes.

The synthesis of ventiloquinone L, the monomer of cardinalin 3

Readily available ethyl-4-acetoxy-6,8-dimethoxynaphthalene-2-carboxylate 27 was converted into 1 -[3-allyl-4(benzyloxy)-6,8-dimethoxy-2-naphthyl)-1-ethanol 31 in seven steps. Subjection of this compound to Wacker oxidation conditions provided 5-benzyloxy-

Leukotriene receptor antagonists. 1. Synthesis and structure-activity relationships of alkoxyacetophenone derivatives

A series of derivatives of 2,4-dihydroxy-3-propylacetophenone were prepared and examined for their ability to block leukotriene D4 (LTD4) induced contraction of guinea pig ileum. Straight-chain carboxylic acids where the carboxyl gro