40829-21-8

Basic information

• Product Name: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide
• Synonyms: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide
• CAS NO: 40829-21-8
• Molecular Weight: 270.331
• Mol File: 40829-21-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide(40829-21-8)
• EPA Substance Registry System: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide(40829-21-8)

Safety Data

• Hazardous Substances Data: 40829-21-8(Hazardous Substances Data)

Upstream product

• 4089-07-0 L-tyrosine ethyl ester monohydrochloride 
• 100-46-9 benzylamine 
• 127485-56-7 Boc-Tyr-OBT 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 60-18-4 L-tyrosine 
• 1164-16-5 Z-L-Tyr-OH 
• 3978-80-1 Boc-Tyr-OH 
• 179631-89-1 tert-butyl (S)-(1-(benzylamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)carbamate 
• 40829-57-0 N-(Carbobenzoxy)-L-tyrosyl-benzylamid 

Downstream Products

• 1370356-27-6 octanedioic acid [1-benzylcarbamoyl-2-(4-hydroxy-phenyl)-ethyl]-amide 
• 1370356-29-8 C₂₄H₃₁N₃O₅ 

Relevant articles and documents

Pd-Catalysed oxidative carbonylation of α-amino amides to hydantoins under mild conditions

The first example of palladium-catalysed oxidative carbonylation of unprotected α-amino amides to hydantoins is described here. The selective synthesis of the target compounds was achieved under mild conditions (1 atm of CO), without ligands and bases. The catalytic system overrode the common reaction pathway that usually leads instead to the formation of symmetrical ureas.

Histone deacetylase inhibitors: Synthesis of tetrapeptide analogue saha/tpx

The inhibition of HDAC (histone deacetylase) activity by specific inhibitors induces growth arrest, differentiation and apoptosis of transformed or everal cancer cells. Some of these inhibitors are in clinical trial at phase I orphase II. The discovery an