40842-04-4 Usage
Description
Ethylene Glycol 1,2-Bis(2-propynyl) Ether, also known as Bis-propargyl-PEG2, is a homobifunctional PEG (Polyethylene Glycol) linker that features two propargyl groups. These propargyl groups are capable of forming triazole linkages with azide-bearing compounds or biomolecules through a copper-catalyzed Click Chemistry process. This unique property makes it a versatile molecule for various applications in different industries.
Uses
Used in Chemical Synthesis:
Ethylene Glycol 1,2-Bis(2-propynyl) Ether is used as a PEG linker for the conjugation of biomolecules and the formation of triazole linkages. The application reason is its ability to facilitate copper-catalyzed Click Chemistry, allowing for the efficient and selective formation of stable triazole rings.
Used in Pharmaceutical Industry:
Ethylene Glycol 1,2-Bis(2-propynyl) Ether is used as a molecular building block for the development of drug conjugates and targeted therapies. The application reason is its compatibility with Click Chemistry, which enables the rapid and efficient synthesis of complex drug molecules with improved pharmacokinetic properties.
Used in Bioconjugation:
Ethylene Glycol 1,2-Bis(2-propynyl) Ether is used as a linker for the attachment of biologically active molecules, such as peptides, proteins, or nucleic acids, to other molecules or surfaces. The application reason is its propensity to form stable triazole linkages, which can enhance the stability and functionality of the resulting bioconjugates.
Used in Material Science:
Ethylene Glycol 1,2-Bis(2-propynyl) Ether is used as a component in the synthesis of advanced materials, such as dendrimers, polymers, and hydrogels. The application reason is its ability to participate in Click Chemistry reactions, allowing for the precise and controlled assembly of complex molecular structures with tailored properties.
Check Digit Verification of cas no
The CAS Registry Mumber 40842-04-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,8,4 and 2 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 40842-04:
(7*4)+(6*0)+(5*8)+(4*4)+(3*2)+(2*0)+(1*4)=94
94 % 10 = 4
So 40842-04-4 is a valid CAS Registry Number.
40842-04-4Relevant articles and documents
Organic-inorganic copolymers with double-decker silsesquioxane in the main chains by polymerization via click chemistry
Wei, Kun,Wang, Lei,Zheng, Sixun
, p. 4221 - 4232 (2013)
A series of novel organic-inorganic copolymers with polyhedral oligomeric silsesquioxane (POSS) in the main chains were synthesized via the copper-catalyzed Huisgen 1,3-dipolar cycloaddition polymerization approach. Toward this end, we synthesized 3,13-az
STAT DEGRADERS AND USES THEREOF
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Paragraph 000999, (2020/10/19)
The present invention provides compounds, compositions thereof, and methods of using the same.
4,7-dioxa-1,9-decane diyne composition
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Paragraph 0015-0016; 0018-0019, (2018/09/08)
The invention discloses a 4,7-dioxa-1,9-decane diyne composition. The structure of the 4,7-dioxa-1,9-decane diyne composition is as following (shown in the description). The composition can serve as acuring agent.
