40851-64-7 Usage
Description
[2-(azidomethyl)phenyl]acetic acid, also known as α-(Azidomethyl)benzylacetic acid, is a chemical compound that features both an azide group and an acetic acid group. The azide group, which consists of three nitrogen atoms, is highly reactive and is commonly utilized as a chemical precursor for the synthesis of other compounds. Meanwhile, the acetic acid group, a carboxylic acid found in vinegar, is known for its widespread use in various industrial applications. [2-(azidomethyl)phenyl]acetic acid holds potential in the realms of organic synthesis, medicinal chemistry, and as a fundamental building block for the creation of novel molecules with tailored properties. Due to the reactivity of the azide group, it is crucial to handle [2-(azidomethyl)phenyl]acetic acid with caution.
Uses
Used in Organic Synthesis:
[2-(azidomethyl)phenyl]acetic acid is used as a chemical precursor for the synthesis of various compounds. Its highly reactive azide group allows for the creation of a diverse range of molecules with specific properties, making it a valuable asset in the field of organic synthesis.
Used in Medicinal Chemistry:
In the domain of medicinal chemistry, [2-(azidomethyl)phenyl]acetic acid serves as a building block for the development of new pharmaceuticals. Its unique structure and reactivity enable the design and synthesis of innovative molecules with potential therapeutic applications.
Used in the Creation of New Molecules:
[2-(azidomethyl)phenyl]acetic acid is used as a fundamental building block for the development of novel molecules with specific properties. Its incorporation into molecular structures can lead to the discovery of new materials and compounds with unique characteristics, further expanding the horizons of chemical research and application.
Check Digit Verification of cas no
The CAS Registry Mumber 40851-64-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,8,5 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 40851-64:
(7*4)+(6*0)+(5*8)+(4*5)+(3*1)+(2*6)+(1*4)=107
107 % 10 = 7
So 40851-64-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3O2/c10-12-11-6-8-4-2-1-3-7(8)5-9(13)14/h1-4H,5-6H2,(H,13,14)
40851-64-7Relevant articles and documents
Schmidt Reaction of ω-Azido Valeryl Chlorides Followed by Intermolecular Trapping of the Rearrangement Ions: Synthesis of Assoanine and Related Pyrrolophenanthridine Alkaloids
DIng, Shao-Lei,Ji, Yang,Su, Yan,Li, Rui,Gu, Peiming
, p. 2012 - 2021 (2019/02/14)
The Schmidt reaction of ω-azido valeryl chlorides in the presence of an additional nucleophile was explored. The arenes, alcohols, and amines were demonstrated as the intermolecular trapping reagents for isocyanate ion and N-acyliminium ion from the Schmidt rearrangement, affording the corresponding products with moderate to excellent yields. Two 2-oxoindoles from the reaction were successfully converted into four natural alkaloids, namely, assoanine, anhydrolycorine, oxoassoanine, and anhydrolycorinone.
(2-Azidomethyl)phenylacetyl as a new, reductively cleavable protecting group for hydroxyl groups in carbohydrate synthesis
Xu, Jinghua,Guo, Zhongwu
, p. 87 - 91 (2007/10/03)
The (2-azidomethyl)phenylacetyl group (AMPA) is described as a new protecting group for carbohydrates. AMPA was introduced to carbohydrate hydroxyl groups in the presence of DCC, while its removal was conveniently achieved via Lindlar catalyst-catalyzed hydrogenation that had no influence on other protecting groups including benzyl, acyl, acetal and ketal.
