40900-00-3Relevant articles and documents
Substrate-Controlled Regioselective Arylations of 2-Indolylmethanols with Indoles: Synthesis of Bis(indolyl)methane and 3,3′-Bisindole Derivatives
He, Ying-Ying,Sun, Xiao-Xue,Li, Guo-Hao,Mei, Guang-Jian,Shi, Feng
, p. 2462 - 2471 (2017)
A substrate-controlled regioselective arylation of 2-indolylmethanols with indoles has been established, which efficiently afforded bis(indolyl)methane and 3,3′-bisindole derivatives in high yields and with a broad substrate scope (up to 98% yield, 36 examples). This approach will not only provide an important strategy for the diversified synthesis of bis(indolyl)methane and 3,3′-bisindole derivatives but also serve as a good example for substrate-controlled regioselective reactions.
The N-tert-butylcarbamoyl directed metalation group for the regiospecific synthesis of 2-substituted pyrroles and indoles
Gharpure,Stoller,Bellamy,Firnau,Snieckus
, p. 1079 - 1082 (2007/10/02)
The N-tert-butylcarbamoyl serves as a useful, readily removable (LiOH/MeOH/THF) new directed metalation group for the synthesis of 2-substituted pyrroles and indoles.
