409366-27-4

Basic information

• Product Name: METHYL(3,5-DICHLORO-4-HYDROXYPHENYL)ACETATE
• Synonyms: METHYL(3,5-DICHLORO-4-HYDROXYPHENYL)ACETATE;(3,5-dichloro-4-hydroxyphenyl)acetic acid Methyl ester;methyl 2-(3,5-dichloro-4-hydroxyphenyl)acetate
• CAS NO: 409366-27-4
• Molecular Formula: C₉H₈Cl₂O₃
• Molecular Weight: 235.06
• Mol File: 409366-27-4.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL(3,5-DICHLORO-4-HYDROXYPHENYL)ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL(3,5-DICHLORO-4-HYDROXYPHENYL)ACETATE(409366-27-4)
• EPA Substance Registry System: METHYL(3,5-DICHLORO-4-HYDROXYPHENYL)ACETATE(409366-27-4)

Safety Data

• Hazardous Substances Data: 409366-27-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 89894-49-5 (3,5-dichloro-4-hydroxyphenyl)acetic acid 
• 3336-41-2 3,5-dichloro-4-hydroxybenzoic acid 
• 59595-92-5 chlorure de dichloro-3,5 hydroxy-4 benzoyle 
• 156-38-7 4-hydroxyphenylacetate 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 788824-07-7 C₁₄H₁₆Cl₂O₅ 

Downstream Products

• 88381-43-5 4-hydroxy-3,5-dichlorophenylacetamide 
• 725239-75-8 [3,5-dichloro-4-(4-methoxy-phenoxy)-phenyl]-acetic acid methyl ester 
• 725239-76-9 [4-(4-benzyloxy-phenoxy)-3,5-dichloro-phenyl]-acetic acid methyl ester 
• 868730-14-7 (3,5-dichloro-4-trifluoromethanesulfonyloxy-phenyl)-acetic acid methyl ester 
• 868730-15-8 [3,5-dichloro-4-(6-methoxy-naphthalen-1-yl)-phenyl]-acetic acid methyl ester 
• 868730-19-2 [4-(5-bromo-6-methoxy-naphthalen-1-yl)-3,5-dichloro-phenyl]-acetic acid methyl ester 
• 788824-08-8 [3,5-dichloro-4-(3-formyl-4-methoxy-phenoxy)-phenyl]-acetic acid methyl ester 
• 788824-22-6 [4-(3-bromo-4-methoxy-phenoxy)-3,5-dichloro-phenyl]-acetic acid methyl ester 
• 788824-09-9 5-(2,6-dichloro-4-methoxycarbonylmethyl-phenoxy)-2-hydroxy-benzoic acid 
• 788824-21-5 [3,5-dichloro-4-(6-methoxy-biphenyl-3-yloxy)-phenyl]-acetic acid methyl ester 

Relevant articles and documents

THYROID HORMONE RECEPTOR AGONISTS

Provided herein are novel thyroid hormone receptor (TR) agonists, e. g., having Formula I, II, or III. Also provided are methods of preparing the novel TR agonists and method of using the novel TR agonists for treating diseases or disorder modulated by TR agonists, such as NAFLD, NASH, diabetes, hyperlipidemia and/or hypercholesterolemia.

Synthesis of (+)-O-methylthalibrine by employing a stereocontrolled Bischler-Napieralski reaction and an electrochemically generated diaryl ether

An efficient electrochemical four-step route was developed for the preparation of diaryl ether derivatives by using halogenation and dehalogenation processes in addition to electrochemical phenolic oxidation and reduction reactions. The synthesis of (+)-O

Electrochemical construction of the diaryl ethers: A synthetic approach to o-methylthalibrine

Electrochemical dimerization of halogenated p-hydroxyphenylacetic acid derivatives followed by Zn reduction provided the corresponding diaryl ethers. Manipulation of the reduction step using several procedures increased its efficiency, which enabled the construction of o-methylthalibrine, an isoquinoline-class alkaloid.