40991-78-4Relevant articles and documents
2-Oxo-Driven N2 Elimination Induced Decarbonylative Cyclization Reaction in Benzotriazoles to 6-Aminophenanthridines
Battula, Satyanarayana,Kumar, Atul,Ahmed, Qazi Naveed,Gupta, Ajai Prakash
, p. 5562 - 5565 (2015)
An efficient functional group induced strategy for the synthesis of 6-aminophenanthridines (6AP) has been developed as a result of an in situ generated novel system "CO-CH(N1N2)". This reaction presents a new mode of N2 ex
Desulfurizing agent for thioamides
Polushina,Zavarzin,Krayushkin,Rodionova,Yarovenko
, p. 383 - 385 (2021/03/03)
Thioamides treated with thionyl chloride in an ionic liquid were successfully converted into amides.
Preparation method of alpha-carbonyl amide compound
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Paragraph 0069-0084, (2021/08/14)
The invention discloses a preparation method of an alpha-carbonyl amide compound. The method comprises the following steps: under the action of a catalyst, taking oxygen as an oxidant, and carrying out oxidative amidation reaction on an alpha-diazoketone compound shown in a chemical formula 2 and a cyclic secondary amine compound shown in a chemical formula 3 in an organic solvent to obtain the alpha-carbonyl amide compound shown in a chemical formula 1, wherein the formulas 1, 2 and 3 are also shown in the speification. According to the preparation method disclosed by the invention, the alpha-carbonyl amide compound is obtained by taking oxygen as the oxidizing agent and catalyzing alpha-diazoketone and cyclic secondary amine to be subjected to oxidative amidation reaction through cuprous iodide, the reaction condition is mild, the reaction time is short, and the byproduct of the reaction is only nitrogen, so that the method is an effective way for green and efficient preparation of the alpha-carbonyl amide compound.