4100-80-5

Basic information

• Product Name: METHYLSUCCINIC ANHYDRIDE
• Synonyms: 2-Methylsuccinic anhydride;3,4-Dihydro-3-methyl-2,5-furandione;3-Methyldihydro-2,5-furandione;3-Methylsuccinic anhydride;Dihydro-3-methyl-2,5-furandione;dihydro-3-methyl-5-furandione;Succinic anhydride, methyl-;PYROTARTARIC ANHYDRIDE
• CAS NO: 4100-80-5
• Molecular Formula: C₅H₆O₃
• Molecular Weight: 114.1
• EINECS: 223-870-5
• Mol File: 4100-80-5.mol
• Article Data: 26

Chemical Properties

• Melting Point: 33-35 °C(lit.)
• Boiling Point: 238-240 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.22 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0411mmHg at 25°C
• Refractive Index: 1.4630 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYLSUCCINIC ANHYDRIDE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYLSUCCINIC ANHYDRIDE(4100-80-5)
• EPA Substance Registry System: METHYLSUCCINIC ANHYDRIDE(4100-80-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 4100-80-5(Hazardous Substances Data)

Usage

Description

METHYLSUCCINIC ANHYDRIDE, also known as 2-Methylsuccinic Anhydride, is a tetrahydrofurandione that is succinic anhydride substituted by a methyl group at position 3. It is a colorless to pale yellow liquid or solid and has been reported to be a pollutant, occurring as a partially oxidized organic component in urban aerosol.

Uses

Used in Environmental Studies:
METHYLSUCCINIC ANHYDRIDE is used as a pollutant indicator for understanding the presence of partially oxidized organic components in urban aerosol. This helps in assessing air quality and the impact of pollution on human health and the environment.
Used in Chemical Research:
METHYLSUCCINIC ANHYDRIDE is used as a chemical compound in various research applications, particularly in the study of organic chemistry and the development of new chemical processes and products. Its unique structure allows for further exploration and potential applications in different industries.

InChI:InChI=1/C5H6O3/c1-3-2-4(6)8-5(3)7/h3H,2H2,1H3/t3-/m0/s1

Upstream product

• 498-21-5 2-methylbutanedioic acid 
• 616-02-4 citraconic acid anhydride 
• 10458-14-7 (2R,5S)-menthone 
• 2170-03-8 itaconic acid anhydride 
• 121-69-7 N,N-dimethyl-aniline 
• 75-36-5 acetyl chloride 
• 82840-54-8 ((C₆H₅)2PCH₂CH₂P(C₆H₅)2)NiCH(CH₃)CH₂COO 
• 201230-82-2 carbon monoxide 
• 64-19-7 acetic acid 
• 82840-52-6 (1,2-bis(diphenylphosphino)ethane)NiCH₂CH₂CH₂COO 
• 3068-88-0 4-methyloxetan-2-one 
• 100-28-7 4-Nitrophenyl isocyanate 
• 75-56-9 methyloxirane 
• 39994-45-1 triethyl propane-1,2,2-tricarboxylate 

Downstream Products

• 4676-51-1 Diethyl 2-methylsuccinate 
• 105475-81-8 4-(3-chloro-4-methoxy-phenyl)-2-methyl-4-oxo-butyric acid 
• 102706-93-4 N-(3-ethoxycarbonyl-butyryl)-N-(3,4-dimethoxy-phenethyl)-glycine ethyl ester 
• 105475-32-9 4-(5-chloro-2-methoxy-phenyl)-2-methyl-4-oxo-butyric acid 
• 115000-98-1 1,4,4-tris-(2,5-dimethoxy-phenyl)-4-hydroxy-2-methyl-butan-1-one 
• 103401-44-1 2,2,5,5-Tetrakis-(2,5-dimethoxy-phenyl)-3-methyl-tetrahydro-furan 
• 91133-69-6 3-methyl-N-phenyl-succinamic acid 
• 3641-24-5 (+/-)-2-methyl-N-phenyl-succinamic acid 
• 874491-38-0 6-(3,4-dichloro-phenyl)-5-methyl-2H-pyridazin-3-one 
• 133101-50-5 γ-(2-methoxyphenyl)-β-methyl-γ-oxobutanoic acid 
• 51037-04-8 2-methyl-4-oxo-4-(p-tolyl)butanoic acid 
• 22895-11-0 3-methyl-4-oxo-4-p-tolyl-butyric acid 
• 33684-15-0 3-methyl-4-[methyl(phenyl)amino]-4-oxobutanoic acid 
• 408308-22-5 2,N-dimethyl-N-phenyl-succinamic acid 

Relevant articles and documents

-

-

Synthesis of Cyclic Anhydrides via Ligand-Enabled C–H Carbonylation of Simple Aliphatic Acids

The development of C(sp3)–H functionalizations of free carboxylic acids has provided a wide range of versatile C?C and C?Y (Y=heteroatom) bond-forming reactions. Additionally, C–H functionalizations have lent themselves to the one-step preparation of a number of valuable synthetic motifs that are often difficult to prepare through conventional methods. Herein, we report a β- or γ-C(sp3)–H carbonylation of free carboxylic acids using Mo(CO)6 as a convenient solid CO source and enabled by a bidentate ligand, leading to convenient syntheses of cyclic anhydrides. Among these, the succinic anhydride products are versatile stepping stones for the mono-selective introduction of various functional groups at the β position of the parent acids by decarboxylative functionalizations, thus providing a divergent strategy to synthesize a myriad of carboxylic acids inaccessible by previous β-C–H activation reactions. The enantioselective carbonylation of free cyclopropanecarboxylic acids has also been achieved using a chiral bidentate thioether ligand.

(Meth) acrylic ester and manufacturing method thereof (by machine translation)

(Meth) acrylic acid ester of [be] hydrophobic properties. (1) (Meth) acrylic ester represented by the formula [a]. R1 Is H or methyl; R3 Alkyl, cycloalkyl, aryl or aralkyl; R21 , R22 , R23 Each independently is H, alkyl or cycloalkyl is not one of at least 2 H; Z1 The divalent chain hydrocarbon substituted of unsubstituted C1 a-20/2, 2 // hetero-substituted of unsubstituted C1 a-20 free of divalent cyclic hydrocarbon or a single bond; Z2 The divalent chain hydrocarbon of C1 c 12 2, Z3 The (R21 R22 R23 ) Coupled with a free cyclic hydrocarbon containing heteroatoms C C - C3 d 10/forming atomic group; n is an integer of 0 - 3; m is an integer of 1 - 18[Drawing] no (by machine translation)