41047-90-9

Basic information

• Product Name: 1,3-Dithiane, 2,2'-(1,3-phenylene)bis-
• CAS NO: 41047-90-9
• Molecular Formula: C14H18S4
• Molecular Weight: 314.561
• Mol File: 41047-90-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-Dithiane, 2,2'-(1,3-phenylene)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dithiane, 2,2'-(1,3-phenylene)bis-(41047-90-9)
• EPA Substance Registry System: 1,3-Dithiane, 2,2'-(1,3-phenylene)bis-(41047-90-9)

Safety Data

• Hazardous Substances Data: 41047-90-9(Hazardous Substances Data)

Upstream product

• 109-80-8 1.3-propanedithiol 
• 626-19-7 Isophthalaldehyde 

Downstream Products

• 949155-92-4 methyl 2-(3-(3-formylphenyl)-3-oxopropyl)benzoate 
• 149968-11-6 methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate 
• 1376678-62-4 C₂₄H₂₈O₂S₄ 

Relevant articles and documents

Practical synthesis of methyl (E)-2-(3-(3-(2-(7-chloro-2-quinolinyl) ethenyl)phenyl)-3-oxopropyl)benzoate, a key intermediate of Montelukast

A novel and practical synthetic route is presented for the preparation of methyl-(E)-2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl) benzoate, the key intermediate of Montelukast, a leukotriene antagonist. The main diarylpropane framework was prepared via a polarity conversation reaction resulting in an acyl anion equivalent followed by a nucleophilic substitution reaction. The overall yield of this approach was 61%. This method is simple for operation and suitable for industrial production.