410545-57-2Relevant articles and documents
POLAR QUINAZOLINES AS LIVER X RECEPTORS ( LXRS ) MODULATORS
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Page/Page column 72, (2010/07/10)
Disclosed are polar quinazoline-based modulators of Liver X receptors (LXRs) and related methods. The modulators include compounds of formula (I): INSERT FORMULA HERE AS IT APPEARS IN WRITTEN FORM IN THE SPECIFICATION (I) in which, R1, R2, R3, R4, R5, R6,
HIV integrase inhibitors: cyclic pyrimidinone compounds
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Page/Page column 19, (2008/06/13)
The invention encompasses a series of pyrimidinone compounds which inhibit HIV integrase and thereby prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses intermediates useful for making the pyrimidone compounds. Additionally, pharmaceutical compositions and methods for treating those infected with HIV are encompassed.