41095-18-5

Basic information

• Product Name: 4-{2-[2,4-dioxopentan-3-ylidene]hydrazinyl}-N-(pyrimidin-2-yl)benzenesulfonamide
• Synonyms: 4-{2-[2,4-dioxopentan-3-ylidene]hydrazinyl}-N-(pyrimidin-2-yl)benzenesulfonamide
• CAS NO: 41095-18-5
• Molecular Weight: 361.381
• Mol File: 41095-18-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-{2-[2,4-dioxopentan-3-ylidene]hydrazinyl}-N-(pyrimidin-2-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{2-[2,4-dioxopentan-3-ylidene]hydrazinyl}-N-(pyrimidin-2-yl)benzenesulfonamide(41095-18-5)
• EPA Substance Registry System: 4-{2-[2,4-dioxopentan-3-ylidene]hydrazinyl}-N-(pyrimidin-2-yl)benzenesulfonamide(41095-18-5)

Safety Data

• Hazardous Substances Data: 41095-18-5(Hazardous Substances Data)

Upstream product

• 131430-29-0 C₁₀H₈ClN₅O₂S 
• 123-54-6 acetylacetone 
• 68-35-9 sulfadiazine 

Downstream Products

• 978-73-4 4-[(3,5-dimethyl-1H-pyrazol-4-yl)diazenyl]-N-(pyrimidin-2-yl)benzenesulfonamide 

Relevant articles and documents

Pyrazole and Nicotinonitrile Derivatives Synthesized from Sulfa Drugs, and Their Antibacterial Activity

Utility of sulfadiazine and sulfaguanidine in synthesis of new series of pyrazoles and 2-pyridones is described. Diazotization of sulfadiazine that results in formation of diazonium salt 2 followed by coupling of the latter with active methylene compounds

Polysubstituted pyrazoles. Part 2: Sulphonamidophenylhydrazone-2-pyrazolin-4-ones and sulphonamidophenylazopyrazoles as potential anticancer agents.

The synthesis of some new derivatives of 1-[4-nitrophenyl]-5-[4-substituted sulphonamidophenylhydrazono]-2-pyrazolin-4-ones and 3,5-dimethyl-4-[4-substituted sulphonamidophenylazo]-pyrazoles is described. Bromination of ethyl 2-[nitrophenylhydrazono]-3-oxobutyrates in dry benzene afforded the 4-bromo derivatives which upon cyclization gave high yields of the 4-hydroxpyrazoles. Many other new intermediates were prepared and the results of the UV and IR spectral studies are discussed.