41128-14-7Relevant articles and documents
Applications of Ytterbium(II) Reagent as Grignard Reagent and Single-Electron Transfer Reagent in the Synthesis of 3-Substituted 2-Oxindoles
Wang, Pengkai,Cao, Xuyan,Zhang, Songlin
supporting information, p. 3836 - 3846 (2021/07/02)
The use of ytterbium(II) reagent as both nucleophilic reagent and single-electron transfer reagent in the reaction of isatin derivatives with ytterbium(II) reagent is reported. From a synthetic point of view, a general, efficient, and experimentally simple one-pot method for the preparation of 3-substituted 2-oxindoles was developed.
Synthetic method of natural product (-)-Psychotriasine
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Paragraph 0009; 0049-0051, (2020/12/15)
The invention relates to a synthetic method of a natural product (-)-Psychotriasine. The method comprises the following steps of: using a compound of a known formula 1 as an initial raw material, carrying out a series of reactions such as triphenylmethyl
Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to N-Unprotected Ketimines: Efficient Synthesis of Cipargamin
Zhu, Jinbin,Huang, Linwei,Dong, Wei,Li, Naikai,Yu, Xingxin,Deng, Wei-Ping,Tang, Wenjun
supporting information, p. 16119 - 16123 (2019/11/03)
Highly enantioselective rhodium-catalyzed addition of arylboroxines to N-unprotected ketimines is realized for the first time by employing chiral BIBOP-type ligands with a Rh loading as low as 1 mol %. A range of chiral α-trifluoromethyl-α,α-diaryl α-tertiary amines or 3-amino-3-aryloxindoles were formed with excellent ee values and yields by employing either WingPhos or PFBO-BIBOP as the ligand. The method has enabled an efficient enantioselective synthesis of cipargamin.