4117-12-8 Usage
Description
rac-Falcarinol is a naturally occurring compound that serves as a covalent cannabinoid CB1 receptor antagonist. It is found in carrots and red ginseng, where it acts as a natural pesticide, protecting the host's roots from various fungal diseases. Additionally, rac-Falcarinol has been associated with nutritional benefits and is believed to reduce the risk of developing specific forms of cancer.
Uses
Used in Pharmaceutical Applications:
rac-Falcarinol is used as a pharmaceutical agent for its pro-allergic effects in the skin. This property makes it a potential candidate for the development of treatments targeting skin-related conditions and allergies.
Used in Agriculture:
As a natural pesticide, rac-Falcarinol is used in agriculture to protect crops, particularly carrots and red ginseng, from fungal diseases. Its application helps maintain the health of the plants and reduces the need for synthetic pesticides, promoting a more sustainable and environmentally friendly approach to crop protection.
Used in Cancer Prevention:
Due to its nutritional benefits and potential cancer risk reduction, rac-Falcarinol is used as a preventive agent against specific forms of cancer. Incorporating it into the diet or developing supplements containing rac-Falcarinol could contribute to improved public health and cancer prevention strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 4117-12-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,1 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4117-12:
(6*4)+(5*1)+(4*1)+(3*7)+(2*1)+(1*2)=58
58 % 10 = 8
So 4117-12-8 is a valid CAS Registry Number.
4117-12-8Relevant articles and documents
A short synthesis of (+) and (-)-falcarinol
McLaughlin, Noel P.,Butler, Eibhlín,Evans, Paul,Brunton, Nigel P.,Koidis, Anastasios,Rai, Dilip K.
scheme or table, p. 9681 - 9687 (2011/02/25)
A short, practical synthesis of the bis-acetylenic natural product falcarinol 1 is reported. This method relies on the alternate functionalisation of bis-trimethylsilylbutadiyne 10. This may be achieved in one-pot, however, better yields were obtained more conventionally. Lipase mediated enzymatic kinetic resolution of the racemic adduct in an organic solvent afforded (+)-1 in 97% enantiomeric excess. The analogous process performed with racemic 3-acetoxy falcarinol 11 under aqueous conditions gave (-)-1. Oxidation of 1 with Dess-Martin periodinane gave falcarinone 2.
