41189-09-7Relevant articles and documents
HYDROXAMATE DERIVATIVES FOR HDAC INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THEREOF
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Paragraph 0584-0586, (2014/10/29)
The present invention relates to a novel hydroxamate derivatives, more specifically, to novel hydroxamate derivatives having inhibitory activity against Histone Deacetylase (HDAC), isomers thereof, pharmaceutically acceptable salts thereof, hydrates or solvates thereof, use for preparing pharmaceutical compositions, pharmaceutical compositions comprising the same, treatment method using said composition, and a preparing method of novel hydroxamate derivatives. The novel selective hydroxamate derivatives having inhibitory activity against Histone Deacetylase (HDAC) compositions can be used for treatment of inflammatory disease, rheumatoid arthritis, or degenerative disease.
SYNTHESES OF CONDENSED TETRACYCLIC AND PENTACYCLIC THIAZOLOPYRIMIDINONES- A NEW CLASS
Babu, B. Ramesh,Ramana, D. V.,Ramadas, S. R.
, p. 175 - 181 (2007/10/02)
Syntheses of tetracyclic and pentacyclic thiazolopyrimidinones (3, 6, 11 and 16) were obtained from the corresponding 2-aminothiazole derivatives (1, 4, 10 and 13) with simple methodology in fairly good yields. Key words: 9-Methyl-6H,11H-benzopyrano4'