4119-18-0

Basic information

• Product Name: 1,2-O-(1-methylethylidene)-3,5-bis-O-[(4-methylphenyl)sulfonyl]pentofuranose
• CAS NO: 4119-18-0
• Molecular Formula: C₂₂H₂₆O₉S₂
• Molecular Weight: 498.5664
• Mol File: 4119-18-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 635.7°C at 760 mmHg
• Flash Point: 338.3°C
• Density: 1.43g/cm³
• Vapor Pressure: 2.27E-15mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: 1,2-O-(1-methylethylidene)-3,5-bis-O-[(4-methylphenyl)sulfonyl]pentofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-O-(1-methylethylidene)-3,5-bis-O-[(4-methylphenyl)sulfonyl]pentofuranose(4119-18-0)
• EPA Substance Registry System: 1,2-O-(1-methylethylidene)-3,5-bis-O-[(4-methylphenyl)sulfonyl]pentofuranose(4119-18-0)

Safety Data

• Hazardous Substances Data: 4119-18-0(Hazardous Substances Data)

Usage

Type of compound

Complex chemical compound

Structure

Sugar-like molecule

Core structure

Pentofuranose ring

Modification at position 2

1-methylethylidene (isopropylidene) group

Modification at positions 3 and 5

Two sulfonyl groups attached

Sulfonyl group detail

[(4-methylphenyl)sulfonyl]

Derivative of

Pentofuranose (a type of sugar)

Unique properties

Provided by the sulfonyl groups

Potential applications

Chemical and biological research

Significance

Precise structure and properties make it interesting and potentially useful for further study

Upstream product

• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 98-59-9 p-toluenesulfonyl chloride 
• 20881-04-3 1,2:3,5-di-O-isopropylidene-D-xylofuranose 
• 532-20-7 D-xylofuranose 

Downstream Products

• 4152-79-8 1,2-O-isopropylidene-5-methyl-5-deoxy-α-D-xylofuranose 
• 79184-24-0 2,5-anhydro-3-O-tosyl-D-xylose diethylacetal 
• 74996-04-6 5-deoxy-5-diphenylphosphino-1,2-O-isopropylidene-α-D-xylofuranose 
• 74996-03-5 5-deoxy-5-diphenylphosphino-1,2-O-isopropylidene-3-O-tosyl-α-D-xylofuranose 
• 77735-72-9 3,4-di-O-tosyl-D-xylose dibenzyl dithioacetal 
• 77735-70-7 3,5-di-O-tosyl-D-xylose diethyl dithioacetal 
• 172039-03-1 (3aR,5R,6S,6aR)-5-(azidomethyl)tetrahydro-2,2-dimethylfuro[2,3-d][1,3]dioxol-6-yl 4-methylbenzenesulfonate 
• 172039-05-3 1,2-di-O-acetyl-5-azido-5-deoxy-3-O-p-toluenesulfonyl-D-xylofuranose 
• 172039-12-2 1-(5-azido-5-deoxy-3-O-p-toluenesulfonyl-β-D-xylofuranosyl)-5-fluorouracil 
• 172039-06-4 1-(2-O-acetyl-5-azido-5-deoxy-3-O-p-toluenesulfonyl-β-D-xylofuranosyl)thymine 
• 172039-08-6 1-(2-O-acetyl-5-azido-5-deoxy-3-O-p-toluenesulfonyl-β-D-xylofuranosyl)-5-fluorouracil 
• 172039-07-5 1-(2-O-acetyl-5-azido-5-deoxy-3-O-p-toluenesulfonyl-β-D-xylofuranosyl)-5-iodouracil 
• 172039-09-7 1-(2-O-acetyl-5-azido-5-deoxy-3-O-p-toluenesulfonyl-β-D-xylofuranosyl)-5-trifluoromethyluracil 
• 20701-43-3 2,5-anhydro-3-O-tosyl-D-xylose dimethyl acetal 

Relevant articles and documents

3-(Dimethylamino)-1-propylamine: A cheap and versatile reagent for removal of byproducts in carbohydrate chemistry

Inexpensive 3-(dimethylamino)-1-propylamine (DMAPA) was found to be effective in anomeric deacylation reactions giving 1-O deprotected sugars in high yield as precursors for the formation of imidate glycosyl donors. DMAPA was also found to be useful for removing excess reagents such as benzoyl chloride, tosyl chloride, and 2,2,2-trifluoro-N-phenylacetimidoyl chloride. The deacylation reaction could be conducted in moist THF and did not require chromatographic purification since an acidic wash was sufficient to remove excess reagent and the formed byproduct.

Radical cyclisation approach for the synthesis of (+)dihydrocanadensolide, (+)dihydrosporothriolide and their C-3 epimers from D-xylose

Intramolecular radical cyclisation protocol on 5-hexenyl systems derived from D-xylose, was utilized for the synthesis of (+)dihydrocanadensolide, (+)-dihydrosporothriolide and their C-3 epimers, wherein a study on the impact of C-2′ stereocentre on radic

Synthesis of 5-amino-5-deoxypentonolactams

5-Azido-5-deoxy-1,2-O-isopropylidene-α-D-xylofuranose (4) and 5-azido-5-deoxy-1,2-O-isopropy-lidene-β-D-arabinofuranose (10) were prepared starting from D-xylose and D-arabinose, respectively. Using the oxidation-reduction way for the C-3 epimerization, 5