41203-27-4Relevant articles and documents
Iron catalyzed halogenation of benzylic aldehydes and ketones
Savela, Risto,W?rn?, Johan,Murzin, Dmitry Yu.,Leino, Reko
, p. 2406 - 2417 (2015/04/14)
A simple and efficient iron-catalyzed method for chlorination of aromatic carbonyl compounds is reported. By using 4-10 mol% Fe(iii) oxo acetate catalyst, prepared by solid state atmospheric oxidation of Fe(ii) acetate, in combination with triethylsilane and chlorotrimethylsilane, hydrosilylation of benzylic carbonyl compounds with subsequent chlorination is achieved within a few hours at room temperature. This new method is mild and rapid compared to the conventional two step approach involving reduction and chlorination reactions in separate stages. Development of synthetic methodology is also supplemented here by kinetic investigation of the reaction mechanism, which supports the tentative mechanisms suggested previously for similar reactions. This journal is
Side Chain Hydroxylation of Aromatic Hydrocarbons by Fungi. Part 2. Isotope Effects and Mechanism
Holland, Herbert L.,Brown, Frances M.,Munoz, Benito,Ninnis, Ronald W.
, p. 1557 - 1564 (2007/10/02)
The benzylic hydroxylation of ethylbenzene, p-diethylbenzene, tetralin, indane, and toluene by the fungi Mortierella isabellina, Cunninghamella echinulata, and Helminthosporium species has been investigated by the use of deuterium-labelled substrates.An i
FUNGAL HYDROXYLATION OF ETHYL BENZENE AND DERIVATIVES
Holland, Herbert L.,Carter, Ian M.,Chenchaiah, P. Chinna,Khan, Shaheer H.,Munoz, Benito,et al.
, p. 6409 - 6412 (2007/10/02)
The fungus Mortierella isabellina converts ethyl benzene and a number of para-substituted derivatives to the corresponding optically active 1-phenylethanols with enantiomeric excesses between 5 and 40percent.Hydrogen removal from the substrate preceeds product formation and is stereochemically independent of it.
