4123-18-6Relevant articles and documents
Amido compounds as RORγt modulators and uses thereof
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Page/Page column 71, (2017/09/30)
Amido compounds are disclosed that have a formula represented by the following: and wherein Cy1, Cy2, n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
Synthesis of New Benzothiazole-2-acrylic Acid Derivatives
Kassem, Emad M. M.,Michael, Josephine M.,El-Masry, A. H.
, p. 424 - 427 (2007/10/03)
Benzothiazole-2-acrylic acid IV reacted with thiourea to give the thiazole derivative V which reacted with different aldehydes to give compounds of the type VI.Also, compound IV reacted with some sulfa drugs and some amines to give amide derivatives of the type VII and IX, respectively.THe prepared compounds showed potential antimicrobial activity. - Key Words: Maleic anhydride; O-Aminothiophenol; Benzothiazole-2-acrylic acid.