412355-81-8

Basic information

• Product Name: 1-(2-Pyrimidinyl)-4-piperidinamine
• Synonyms: 1-(2-PYRIMIDINYL)-4-PIPERIDINAMINE;1-pyrimidin-2-ylpiperidin-4-amine(SALTDATA: 2HCl);4-Amino-1-(Pyrimidin-2-yl)piperidine;1-pyrimidin-2-ylpiperidin-4-amine 2HCl;4-AMino-1-(2-pyriMidinyl)piperidine
• CAS NO: 412355-81-8
• Molecular Formula: C₉H₁₄N₄
• Molecular Weight: 178.23
• Mol File: 412355-81-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 340.6 °C at 760 mmHg
• Flash Point: 159.8 °C
• Appearance: /
• Density: 1.144 g/cm³
• Vapor Pressure: 8.5E-05mmHg at 25°C
• Refractive Index: 1.566
• CAS DataBase Reference: 1-(2-Pyrimidinyl)-4-piperidinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Pyrimidinyl)-4-piperidinamine(412355-81-8)
• EPA Substance Registry System: 1-(2-Pyrimidinyl)-4-piperidinamine(412355-81-8)

Safety Data

• Hazardous Substances Data: 412355-81-8(Hazardous Substances Data)

Usage

General Description

1-(2-Pyrimidinyl)-4-piperidinamine is a chemical compound with the molecular formula C9H14N4. It is commonly referred to as P-PDA and is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. P-PDA is a white to off-white solid that is soluble in organic solvents and has a melting point of 157-159°C. It is primarily used as a building block in the production of pyrimidine-based drugs and other heterocyclic compounds. P-PDA has also been studied for its potential antileishmanial and antimicrobial properties, making it a versatile and valuable chemical in the pharmaceutical and agrochemical industries.

InChI:InChI=1/C9H14N4/c10-8-2-6-13(7-3-8)9-11-4-1-5-12-9/h1,4-5,8H,2-3,6-7,10H2

Upstream product

• 180695-80-1 tert-butyl 4-azidopiperidine-1-carboxylate 
• 1452394-23-8 2-(4-azidopiperidin-1-yl)pyrimidine 
• 73874-95-0 (piperidin-4-yl)carbamic acid tert-butyl ester 

Downstream Products

• 1025392-74-8 (4-bromo-2-nitro-phenyl)-(1-pyrimidin-2-yl-piperidin-4-yl)-amine 
• 1033844-52-8 6-(2-hydroxyphenyl)-N-(1-pyrimidin-2-ylpiperidin-4-yl)nicotinamide 

Relevant articles and documents

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