4124-63-4

Basic information

• Product Name: mercaptoacetaldehyde
• Synonyms: mercaptoacetaldehyde;2-Mercaptoacetaldehyde;Einecs 223-929-5
• CAS NO: 4124-63-4
• Molecular Formula: C₂H₄OS
• Molecular Weight: 76.11756
• EINECS: 223-929-5
• Mol File: 4124-63-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 150-152 °C
• Boiling Point: 112.8°Cat760mmHg
• Flash Point: 22°C
• Appearance: /
• Density: 1.043g/cm³
• Vapor Pressure: 21.4mmHg at 25°C
• Refractive Index: 1.444
• PKA: 8.23±0.10(Predicted)
• CAS DataBase Reference: mercaptoacetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: mercaptoacetaldehyde(4124-63-4)
• EPA Substance Registry System: mercaptoacetaldehyde(4124-63-4)

Safety Data

• Hazardous Substances Data: 4124-63-4(Hazardous Substances Data)

Usage

General Description

Mercaptoacetaldehyde, also known as 2-Thiopropanal or 2-Sulfanylpropanal, is a chemical compound with the molecular formula C3H6OS. It belongs to the family of organic compounds known as thioaldehydes and thiones. Mercaptoacetaldehyde can be found in numerous applications within the chemical industry, particularly in organosulfur chemistry. It is often used as a precursor to other chemicals and as an important reactant in various synthetic reactions. Despite its extensive uses, it must be handled with care due to its flammability and potential health risks, such as skin and eye irritation.

InChI:InChI=1/C2H4OS/c3-1-2-4/h1,4H,2H2

Upstream product

• 40018-26-6 1,4-dithiane-2,5-diol 
• 921-01-7 rac-cysteine 
• 107-20-0 2-chloroethanal 

Downstream Products

• 20915-45-1 glyoxal bis(N-methyl-N-phenylhydrazone) 
• 40700-11-6 3-phenyl-3H-thiazole-2-selone 
• 79217-03-1 4-Amino-5-formyl-2-phenyl-thiophen-3-carbonitril 
• 463-51-4 Ketene 
• 75-07-0 acetaldehyde 
• 66867-06-9 2-methyl-2,5-dihydro-thiazole 
• 108284-82-8 2-ethyl-2,5-dihydro-thiazole 
• 66692-88-4 2,2-dimethyl-2,5-dihydrothiazole 
• 66867-03-6 2-Methyl-2-aethyl-thiazolin-(3) 
• 1144108-41-7 C₁₅H₂₀N₂O₂S 
• 1144108-45-1 C₂₀H₂₈N₄O₃S 
• 1144108-42-8 C₁₂H₁₃N₃O₅S 
• 96-50-4 2-thiazolylamine 
• 4570-45-0 2-amino-1,3-oxazole 

Relevant articles and documents

Facile synthesis of 3-substituted thiazolo[2,3-α]tetrahydroisoquinolines

It was found that 4-hydroxy-2-butenoic ester (11) could not react with 3,4-dihydro-isoquinoline (4a). Individual addition reactions of γ-mercapto-α,β-unsaturated esters (18) and-unsaturated amide (19) with 3,4-dihydroisoquinolines (4) were carried out under appropriate conditions to provide the corresponding thiazolo[2,3-α]isoquinoline derivatives with good yields (up to 87%) and significant diastereomeric selectivity. The mechanism of the crucial reaction was discussed.

Deposition of new thia-containing Schiff-base iron (III) complexes onto carbon nanotube-modified glassy carbon electrodes as a biosensor for electrooxidation and determination of amino acids

Multiwall carbon nanotubes (MWCNTs) were used as an immobilization matrix to incorporate an Fe (III)-Schiff base complex as an electron-transfer mediator onto a glassy carbon electrode surface. First, the preheated glassy carbon was subjected to abrasive immobilization of MWCNTs by gently rubbing the electrode surface on filter paper supporting the carbon nanotubes. Second, the electrode surface was modified by casting 100 μL of an Fe (III)-complex solution (0.01 M in ACN). The cyclic voltammograms of the modified electrode in an aqueous solution displayed a pair of well-defined, stable and nearly reversible reductive oxidation redox systems with surface confined characteristics. Combinations of unique electronic and electrocatalytic properties of MWCNTs and Fe (III)-Schiff base complexes resulted in a remarkable synergistic augmentation of the response. The electrochemical behavior and stability of the modified electrode in aqueous solutions at pH 1-9 were characterized by cyclic voltammetry. The apparent electron transfer rate constant (Ks) and transfer coefficient (a) were determined by cyclic voltammetry and were approximately 7 s-1 and 0.55, respectively. The modified electrodes showed excellent catalytic activity towards the oxidation of amino acids at an unusually positive potential in acidic solution. They also displayed inherent stability at a wide pH range, fast response time, high sensitivity, low detection limit and had a remarkably positive potential oxidation of amino acids that decreased the effect of interferences in analysis. The linear concentration range, limits of detection (LOD), limits of quantization (LOQ) and relative standard deviation of the proposed sensor for the amino acid detection were 1-55,000, 1.10-13.70, 2.79-27.14 and 1.30-5.11, respectively.