41240-77-1

Basic information

• Product Name: N-[4-(hexyloxy)phenyl]acetamide
• Synonyms: N-[4-(hexyloxy)phenyl]acetamide;N-(4-hexoxyphenyl)acetamide
• CAS NO: 41240-77-1
• Molecular Formula: C₁₄H₂₁NO₂
• Molecular Weight: 235.32204
• EINECS: 255-276-7
• Mol File: 41240-77-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 401.3°Cat760mmHg
• Flash Point: 196.5°C
• Appearance: /
• Density: 1.027g/cm³
• Vapor Pressure: 1.19E-06mmHg at 25°C
• Refractive Index: 1.526
• CAS DataBase Reference: N-[4-(hexyloxy)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-(hexyloxy)phenyl]acetamide(41240-77-1)
• EPA Substance Registry System: N-[4-(hexyloxy)phenyl]acetamide(41240-77-1)

Safety Data

• Hazardous Substances Data: 41240-77-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H21NO2/c1-3-4-5-6-11-17-14-9-7-13(8-10-14)15-12(2)16/h7-10H,3-6,11H2,1-2H3,(H,15,16)

Upstream product

• 2009-83-8 6-chloro-1-hexanol 
• 103-90-2 4-acetaminophenol 
• 4286-55-9 1-bromo-6-hexanol 
• 111-25-1 1-bromo-hexane 
• 39905-57-2 4-(n-hexyloxy)aniline 
• 108-24-7 acetic anhydride 

Downstream Products

• 57666-61-2 4-hexyloxyaniline hydrochloride 
• 39905-57-2 4-(n-hexyloxy)aniline 
• 1396273-28-1 C₂₄H₂₅NO₃S 
• 1158909-71-7 N,N-di(4-n-hexyloxyphenyl)amine 
• 141510-20-5 4-[2-[4-(hexyloxy)phenyl]diazen-1-yl]phenol 

Relevant articles and documents

A mitochondria-targeted mass spectrometry probe to detect glyoxals: Implications for diabetes

The glycation of protein and nucleic acids that occurs as a consequence of hyperglycemia disrupts cell function and contributes to many pathologies, including those associated with diabetes and aging. Intracellular glycation occurs after the generation of the reactive 1,2-dicarbonyls methylglyoxal and glyoxal, and disruption of mitochondrial function is associated with hyperglycemia. However, the contribution of these reactive dicarbonyls to mitochondrial damage in pathology is unclear owing to uncertainties about their levels within mitochondria in cells and in vivo. To address this we have developed a mitochondria-targeted reagent (MitoG) designed to assess the levels of mitochondrial dicarbonyls within cells. MitoG comprises a lipophilic triphenylphosphonium cationic function, which directs the molecules to mitochondria within cells, and an o-phenylenediamine moiety that reacts with dicarbonyls to give distinctive and stable products. The extent of accumulation of these diagnostic heterocyclic products can be readily and sensitively quantified by liquid chromatography-tandem mass spectrometry, enabling changes to be determined. Using the MitoG-based analysis we assessed the formation of methylglyoxal and glyoxal in response to hyperglycemia in cells in culture and in the Akita mouse model of diabetes in vivo. These findings indicated that the levels of methylglyoxal and glyoxal within mitochondria increase during hyperglycemia both in cells and in vivo, suggesting that they can contribute to the pathological mitochondrial dysfunction that occurs in diabetes and aging.

Columnar self-assembly of bowl shaped fluorescent liquid crystals based on calix[4]arene with Schiff base units

A new family of bowl-shaped molecules with a calix[4]arene rigid core and appended on four-sides, that display a wide range of hexagonal columnar phases, has been synthesised and well characterized. The thermal behaviours of the present compounds were established using a combination of polarising optical microscopy (POM), differential scanning calorimetry (DSC) and a high-temperature powder X-ray diffraction method (XRD). It is found that all of the synthesised materials show an enantiotropic hexagonal columnar liquid crystal phase. The structural and conformation characterization of these newly synthesised compounds was achieved by FT-IR, 1H NMR, and 13C NMR spectroscopy. All of the synthesised compounds exhibited good blue luminescence in solution under long wavelength UV light. To explore the structure property correlations, the alkoxy side chain group was varied from a lower alkyl spacer to a higher alkyl spacer on the lower rim of the calix[4]arene. The present research specified that the introduction of linking groups on the lower rim with an n-alkoxy side group is an influential approach to obtaining a supramolecular bowl shape liquid crystal which has good thermal and photophysical behaviour.

AZOBENZENE COMPOUND AND HEAT PUMP SYSTEM USING THE SAME

PROBLEM TO BE SOLVED: To provide an azobenzene compound capable of repeated structural changes without heating, and a heat pump system using the same. SOLUTION: An azobenzene compound represented by the general formula (1) and undergoing cis-trans isomerization reaction upon light irradiation is used as a heat medium of a heat pump system. In the formula, at least one of R1 to R3 is (CH2CH2O)n-R10; R4 is R11, O-R11, NH-R11, or COO-R11; X- is Cl-, Br-, I-, BF4-, PF6-, CH3(CH2)nSO3-, TsO-, (YSO2)2 N-, or (NC)2 N-; n is an integer between 0 and 2; and Y is F, CF3, or C2F5. COPYRIGHT: (C)2015,JPO&INPIT