4131-04-8

Basic information

• Product Name: Methanone, (4-methoxyphenyl)(2,4,6-trimethoxyphenyl)-
• CAS NO: 4131-04-8
• Molecular Formula: C17H18O5
• Molecular Weight: 302.327
• Mol File: 4131-04-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanone, (4-methoxyphenyl)(2,4,6-trimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-methoxyphenyl)(2,4,6-trimethoxyphenyl)-(4131-04-8)
• EPA Substance Registry System: Methanone, (4-methoxyphenyl)(2,4,6-trimethoxyphenyl)-(4131-04-8)

Safety Data

• Hazardous Substances Data: 4131-04-8(Hazardous Substances Data)

Upstream product

• 621-23-8 1,2,3-trimethoxybenzene 
• 100-07-2 4-methoxy-benzoyl chloride 
• 7446-70-0 aluminium trichloride 
• 201230-82-2 carbon monoxide 
• 2510-49-8 2-iodo-1,3,5-trimethoxybenzene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 58948-36-0 2-(4-Methoxyphenyl)-1,3-benzoxathiolium tetrafluoroborate 
• 111149-11-2 2-(4-Methoxy-phenyl)-2-(2,4,6-trimethoxy-phenyl)-benzo[1,3]oxathiole 

Downstream Products

• 4254-46-0 2,4,6,4'-tetramethoxy-thiobenzophenone 
• 670249-11-3 2,4,6,4'-Tetramethoxy-benzhydrol 
• 6016-67-7 3.5-Dichlor-2.4.4'.6-tetramethoxy-benzophenon 

Relevant articles and documents

Hexafluoro-2-propanol-Promoted Intermolecular Friedel-Crafts Acylation Reaction

The intermolecular Friedel-Crafts acylation was carried out in hexafluoro-2-propanol to yield aryl and heteroaryl ketones at room temperature without any additional reagents.

Carbonylative cross-coupling of ortho-disubstituted aryl iodides. Convenient synthesis of sterically hindered aryl ketones

(Chemical Equation Presented) A mild and general protocol for the carbonylative cross-coupling of sterically hindered ortho-disubstituted aryl iodides is reported. Carbonylative Suzuki-Miyaura couplings of a variety of aryl boronic acids provide an array of substituted biaryl ketones in modest to excellent yield. A carbonylative Negishi coupling that utilizes alkynyl nucleophiles is also described.