41412-79-7Relevant articles and documents
Original TDAE strategy using propargylic chloride: Rapid access to 1,4-diarylbut-3-ynol derivatives
Roche, Manon,Terme, Thierry,Vanelle, Patrice
, p. 1540 - 1548 (2013/04/10)
We report herein the first synthesis of propargylic alcohols using an organic reducing agent. Diarylbutynol derivatives are formed in moderate to good yields under mild conditions from the reaction of 1-(3-chloroprop-1-ynyl)-4- nitrobenzene with various aromatic aldehydes using tetrakis(dimethylamino) ethylene (TDAE) as reductant.