4146-24-1

Basic information

• Product Name: 6-Chloro-2-methyl-benzothiazole
• Synonyms: 6-Chloro-2-methyl-benzothiazole;Benzothiazole, 6-chloro-2-methyl- (6CI,7CI,8CI,9CI);2-Methyl-6-chlorobenzothiazole;Benzothiazole, 6-chloro-2-Methyl-;6-Chloro-2-Methylbenzo[d]thiazole
• CAS NO: 4146-24-1
• Molecular Formula: C₈H₆ClNS
• Molecular Weight: 183.65794
• Product Categories: BENZOTHIAZOLE
• Mol File: 4146-24-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 276.8 °C at 760mmHg
• Flash Point: 121.2 °C
• Appearance: /
• Density: 1.365 g/cm³
• Vapor Pressure: 0.0079mmHg at 25°C
• Refractive Index: 1.67
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-Chloro-2-methyl-benzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-2-methyl-benzothiazole(4146-24-1)
• EPA Substance Registry System: 6-Chloro-2-methyl-benzothiazole(4146-24-1)

Safety Data

• Hazardous Substances Data: 4146-24-1(Hazardous Substances Data)

Usage

Chemical Properties

Yellow solid

InChI:InChI=1/C8H6ClNS/c1-5-10-7-3-2-6(9)4-8(7)11-5/h2-4H,1H3

Upstream product

• 23474-98-8 2-amino-5-chlorobenzenethiol 
• 62-55-5 thioacetamide 
• 127-19-5 N,N-dimethyl acetamide 
• 2466-76-4 N-Acetylimidazole 

Downstream Products

• 107611-13-2 6-chloro-2-trans-styryl-benzothiazole 
• 74214-69-0 4-[trans-2-(6-chloro-benzothiazol-2-yl)-vinyl]-N,N-dimethyl-aniline 
• 50739-39-4 2-(bromomethyl)-6-chloro-1,3-benzothiazole 
• 23474-98-8 2-amino-5-chlorobenzenethiol 
• 55202-19-2 2-Methyl-5,6-dichlor-benzothiazol 
• 34257-30-2 7-Amino-6-chlor-2-methyl-benzthiazol 
• 1316859-91-2 2-methyl-6-(1-(2-nitrophenyl)-2-phenylethyl)benzo[d]thiazole 
• 1316859-60-5 2-methyl-6-(2-nitrobenzyl)benzo[d]thiazole 
• 42474-60-2 2-methylbenzo[d]thiazole-6-carbonitrile 
• 107559-02-4 2-methyl-6-phenylbenzothiazole 

Relevant articles and documents

Efficient CDI/CH3SO3H-catalyzed, microwave-assisted synthesis of 2-substituted benzothiazoles

CDI combined with CH3SO3H was found to be highly effective for the cyclization of 2-aminothiophenol derivatives with carboxylic acids under MW condition. Fourteen benzothiazole derivatives were synthesized in good yield and their structures were characterized by1H-NMR,13C-NMR, IR and mass spectrometry. This simple, rapid synthetic method is believed to provide a useful process for the synthesis of 2-substituted benzothiazole compounds.

Synthesis method of 2-substituted benzoxazole, 2-substituted benzothiazole and derivatives thereof

The invention provides a synthesis method of 2-substituted benzoxazole, 2-substituted benzothiazole and derivatives thereof. In the method, through ortho-aminophenol/2-aminothiophenol cyclization catalyzed by imidazole hydrochloride, synthesis of functionalized 2-substituted benzoxazole and 2-substituted benzothiazole is realized; the method is simple, economical and high in practicality. No othercatalysts or additives are used, the synthesis method ensures good functional group tolerance and excellent yield and purity, the reaction time is short, no harsh reaction conditions are needed, andthe method is suitable for industrial production.