41468-11-5

Basic information

• Product Name: Benzenemethanesulfonic acid, a-hydroxy-4-nitro-, monosodium salt
• CAS NO: 41468-11-5
• Molecular Formula: C7H7NO6S.Na
• Molecular Weight: 255.184
• Mol File: 41468-11-5.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzenemethanesulfonic acid, a-hydroxy-4-nitro-, monosodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanesulfonic acid, a-hydroxy-4-nitro-, monosodium salt(41468-11-5)
• EPA Substance Registry System: Benzenemethanesulfonic acid, a-hydroxy-4-nitro-, monosodium salt(41468-11-5)

Safety Data

• Hazardous Substances Data: 41468-11-5(Hazardous Substances Data)

Upstream product

• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 555-16-8 4-nitrobenzaldehdye 
• 882-06-4 4-nitro-trans-cinnamic acid 
• 14856-73-6 4-nitrobenzyl trimethylsilyl ether 
• 123371-45-9 ethyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate 
• 7152-75-2 4-(4-nitrobenzylidene)-2-phenyl-5(4H) oxazolone 
• 69570-99-6 2-(4-nitrophenyl)-1H-benzimidazole-5-carboxylic acid 
• 1772-39-0 5-nitro-2-(4-nitrophenyl)-1H-benzimidazole 
• 355816-01-2 3,4-dimethyl-N-(4-nitrobenzyl)aniline 
• 1037303-37-9 4-chloro-3-(cyclohexylmethyl)-2-(4-nitrophenyl)-3H-imidazo[4,5-g]quinoline 
• 1377136-59-8 ethyl 2-(4-nitrophenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate 
• 1621480-72-5 8-chloro-N^6-(4-nitrobenzylidene)quinoline-6,7-diamine 
• 177703-41-2 5-(4-nitro-benzylidene)-thiazolidine-2,4-dione 
• 3717-95-1 1,3-dimethyl-2-(4-nitrophenyl)-1H-benzimidazol-3-ium iodide 
• 3718-03-4 1-methyl-2-(4-nitrophenyl)-1H-benzimidazole 

Relevant articles and documents

Bisulfite Addition Compounds as Substrates for Reductive Aminations in Water

Highly valued products resulting from reductive aminations utilizing shelf-stable bisulfite addition compounds of aldehydes can be made under aqueous micellar catalysis conditions. Readily available α-picolineborane serves as the stoichiometric hydride source. Recycling of the aqueous reaction medium is easily accomplished, and several applications to targets in the pharmaceutical industry are documented.

Reduction of Weinreb amides to aldehydes under ambient conditions with magnesium borohydride reagents Dedicated to the memory of Professor Sheldon Shore

Chloromagnesium dimethylaminoborohydride (ClMg+ [H3BNMe2]-, MgAB) is an analogue of the versatile lithium dialkylaminoborohydrides (LAB reagents), prepared by the reaction of dimethylamine-borane with methylmagnesium chloride. MgAB is a partial reducing agent for Weinreb amides under ambient conditions and is complementary to the commonly utilized lithium aluminum hydride (LiAlH4) and diisobutylaluminum hydride (DIBAL) reagents, while exhibiting enhanced chemoselectivity. To prevent over-reduction, the aldehyde products are readily isolated in good yields by forming the sodium bisulfite adducts. Aldehyde products can both be stored and later used as the bisulfite adducts, or can be regenerated from the bisulfite adducts by treatment with aqueous formaldehyde.

Phosphoryl chloride mediated synthesis of 5-arylidene-2,4- thiazolidinediones derivatives via aromatic bisulfite adducts

The carbon-carbon bond formation by the condensation of bisulfite adduct of aromatic aldehydes with thiazolidine-2, 4-dione to furnish 5-arylidene-2,4- thiazolidinedione's has been investigated. This novel methodology was applied to convert substituted aryl bisulfite adducts to corresponding 5-arylidene-2,4-thiazolidinedione's with POCl3 in less-polar solvents such as toluene, chlorobenzene and o-xylene. 5-(4-methoxybenzylidene) thiazolidine-2,4-dione and 5-(4-ethoxybenzylidene)thiazolidine-2,4-dione were obtained in good yields.