41493-89-4Relevant articles and documents
Having pharmaceutical activity of the benzoxazine and pyrazole - calcium complex preparation method
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Paragraph 0020; 0027; 0028, (2017/11/29)
The present invention discloses a pharmaceutical active of the benzoxazine and pyrazole - calcium complex preparation method, which belongs to the technical field of drug synthesis. Technical proposal of the invention points are: The invention compared with the prior art has the following advantages: the invention synthetic method is simple, novel and molecular structure of the obtained compound with anti-platelet aggregation effect ticlopidine quite.
Effect of polyamine homologation on the transport and biological properties of heterocyclic amidines
Delcros, Jean-Guy,Tomasi, Sophie,Duhieu, Stéphane,Foucault, Marine,Martin, Bénédicte,Le Roch, Myriam,Eifler-Lima, Vera,Renault, Jacques,Uriac, Philippe
, p. 232 - 245 (2007/10/03)
Five sets of heterocyclic derivatives of various sizes and complexities coupled by an amidine function to putrescine, spermidine, or spermine were prepared. They were essentially tested to determine the influence of the polyamine chain on their cellular t