41505-91-3

Basic information

• Product Name: methyl 2-(fluorosulfonyl)acetate
• Synonyms: methyl 2-(fluorosulfonyl)acetate
• CAS NO: 41505-91-3
• Molecular Weight: 156.135
• Mol File: 41505-91-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-(fluorosulfonyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(fluorosulfonyl)acetate(41505-91-3)
• EPA Substance Registry System: methyl 2-(fluorosulfonyl)acetate(41505-91-3)

Safety Data

• Hazardous Substances Data: 41505-91-3(Hazardous Substances Data)

Upstream product

• 56146-83-9 chlorosulfonyl-acetic acid methyl ester 

Downstream Products

• 4271-99-2 trimethyl trans-aconitate 

Relevant articles and documents

Clickable transformation of nitriles (RCN) to oxazolyl sulfonyl fluoride warheads

The protocol for simple, efficient, and mild synthesis of oxazolyl sulfonyl fluorides was developed through Rh2(OAc)4-catalyzed annulation of methyl-2-diazo-2-(fluorosulfonyl)acetate (MDF) or its ethyl ester derivative with nitriles. This practical method provides a general and direct route to a unique class of highly functionalized oxazolyl-decorated sulfonyl fluoride warheads with great potential in medicinal chemistry, chemical biology, and drug discovery.