4151-45-5Relevant articles and documents
Kinetics and mechanism of the basic hydrolysis of indomethacin and related compounds: A reevaluation
Cipiciani,Ebert,Linda,Rubessa,Savelli
, p. 1075 - 1076 (2007/10/02)
The kinetics of the hydrolysis of indomethacin and related compounds were studied in an alkaline medium at 25°. The pseudo-first-order rate constants were evaluated from log absorbance versus time plots in the ultraviolet. These compounds showed a second-order rate constant at low concentrations of hydroxide ion and a first-order rate constant at higher concentrations of hydroxide ion.