41536-89-4

Basic information

• Product Name: N-[(5R)-2ξ-(2,4-dinitro-benzoyloxy)-3,3-dimethyl-4t,7-dioxo-(5rH)-4λ⁴-thia-1-aza-bicyclo[3.2.0]hept-6t-yl]-2-phenyl-acetamide
• Synonyms: N-[(5R)-2ξ-(2,4-dinitro-benzoyloxy)-3,3-dimethyl-4t,7-dioxo-(5rH)-4λ⁴-thia-1-aza-bicyclo[3.2.0]hept-6t-yl]-2-phenyl-acetamide
• CAS NO: 41536-89-4
• Molecular Weight: 516.488
• Mol File: 41536-89-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[(5R)-2ξ-(2,4-dinitro-benzoyloxy)-3,3-dimethyl-4t,7-dioxo-(5rH)-4λ⁴-thia-1-aza-bicyclo[3.2.0]hept-6t-yl]-2-phenyl-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(5R)-2ξ-(2,4-dinitro-benzoyloxy)-3,3-dimethyl-4t,7-dioxo-(5rH)-4λ⁴-thia-1-aza-bicyclo[3.2.0]hept-6t-yl]-2-phenyl-acetamide(41536-89-4)
• EPA Substance Registry System: N-[(5R)-2ξ-(2,4-dinitro-benzoyloxy)-3,3-dimethyl-4t,7-dioxo-(5rH)-4λ⁴-thia-1-aza-bicyclo[3.2.0]hept-6t-yl]-2-phenyl-acetamide(41536-89-4)

Safety Data

• Hazardous Substances Data: 41536-89-4(Hazardous Substances Data)

Upstream product

• 34103-64-5 N-((5R)-2c-hydroxy-3,3-dimethyl-4t,7-dioxo-(5rH)-4λ⁴-thia-1-aza-bicyclo[3.2.0]hept-6t-yl)-2-phenyl-acetamide 
• 20195-22-6 2,4-dinitrobenzoyl chloride 

Downstream Products

• 34103-64-5 N-((5R)-2c-hydroxy-3,3-dimethyl-4t,7-dioxo-(5rH)-4λ⁴-thia-1-aza-bicyclo[3.2.0]hept-6t-yl)-2-phenyl-acetamide 
• 41536-81-6 N-[(5R)-2c-(3-chloro-benzoyloxy)-3,3-dimethyl-4t,7-dioxo-(5rH)-4λ⁴-thia-1-aza-bicyclo[3.2.0]hept-6t-yl]-2-phenyl-acetamide 
• 41536-81-6 N-[(5R)-2c-(3-chloro-benzoyloxy)-3,3-dimethyl-4t,7-dioxo-(5rH)-4λ⁴-thia-1-aza-bicyclo[3.2.0]hept-6c-yl]-2-phenyl-acetamide 

Relevant articles and documents

Process for the preparation of 3-hydroxy penam-1-oxides and derivatives thereof

The invention relates to a novel process for the preparation of 3-hydroxy penam-1-oxides and esterified and etherified derivatives thereof. The process involves reaction of a penam-1-oxide mixed anhydride with a peracid followed by rearrangement and decarboxylation of the product initially formed to yield a 3-aroyloxy-penam-1-oxide. The latter compound may if desired subsequently be subjected to reductive cleavage to yield a 3-hydroxy compound, such reductive cleavage conveniently being effected by means of zinc and an ammonium salt under neutral or acidic conditions. The compounds prepared by the process of this invention are useful as intermediates in the preparation of antibiotics.