41575-23-9 Usage
Compound class
Isoindolinone compounds 2-(2-chloroethyl)isoindolin-1-one belongs to a specific group of chemical compounds known as isoindolinones.
Physical appearance
White solid substance This describes the color and physical state of 2-(2-chloroethyl)isoindolin-1-one.
Solubility
Soluble in organic solvents 2-(2-chloroethyl)isoindolin-1-one can dissolve in certain organic solvents, which is important for its applications in chemical reactions and synthesis.
Odor
Characteristic odor 2-(2-chloroethyl)isoindolin-1-one has a distinct smell, which may be relevant for handling and storage purposes.
Use in pharmaceuticals and agrochemicals
Building block for biologically active compounds 2-(2-chloroethyl)isoindolin-1-one is used as a starting material in the synthesis of various pharmaceuticals and agrochemicals, as it can be converted into compounds with biological activity.
Use as a reagent
Organic chemical reactions 2-(2-chloroethyl)isoindolin-1-one can be used as a reagent in organic chemical reactions, facilitating the formation of desired products.
Research chemical
Medicinal chemistry As a research chemical, 2-(2-chloroethyl)isoindolin-1-one is valuable for studying and understanding the properties and behavior of isoindolinone compounds in the context of medicinal chemistry.
Potential applications
New materials development and organic synthesis Due to its unique chemical properties, 2-(2-chloroethyl)isoindolin-1-one may have future applications in the development of new materials and in the field of organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 41575-23-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,5,7 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 41575-23:
(7*4)+(6*1)+(5*5)+(4*7)+(3*5)+(2*2)+(1*3)=109
109 % 10 = 9
So 41575-23-9 is a valid CAS Registry Number.
41575-23-9Relevant articles and documents
-
Murata
, p. 1752 (1973)
-
Complementary synthetic approaches to constitutionally diverse N-aminoalkylated isoindolinones: Application to the synthesis of falipamil and 5-HT1A receptor ligand analogues
Lorion, Magali,Couture, Axel,Deniau, Eric,Grandclaudon, Pierre
experimental part, p. 1897 - 1903 (2010/02/16)
Different synthetic approaches for the elaboration of poly and diversely substituted isoindolinones tailed with constitutionally diverse aminoalkylated chains have been developed. The key step is based upon the preliminary assembly of the isoindolinone te
Effect of linking bridge modifications on the antipsychotic profile of some phthalimide and isoindolinone derivatives
Norman, Mark H.,Minick, Douglas J.,Rigdon, Greg C.
, p. 149 - 157 (2007/10/03)
A series of phthalimide and isoindolinone derivatives bridged to 4-(1,2- benzisothiazol-3-yl)-1-piperazinyl was prepared. The compounds were evaluated in vitro at dopamine D2 and serotonin 5-HT(1a) and 5-HT2 receptors and in vivo for their ability to antagonize the apomorphine-induced climbing response in mice. The effects of bridge length and conformation on the biological activity of these potential antipsychotic agents are discussed. A four-carbon spacer provided optimal activity within the two homologous series. Conformational investigations of the lead compound, isoindolinone 2, were conducted in an attempt to account for the superior activity observed for the butyl derivatives. On the basis of NMR and molecular modeling studies, two types of folded structures were proposed and several conformationally restrained analogues were synthesized. In general, restrictions incorporated within the linking bridge were detrimental to activity.
