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416877-62-8

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416877-62-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 416877-62-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,1,6,8,7 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 416877-62:
(8*4)+(7*1)+(6*6)+(5*8)+(4*7)+(3*7)+(2*6)+(1*2)=178
178 % 10 = 8
So 416877-62-8 is a valid CAS Registry Number.

416877-62-8Relevant articles and documents

Synthesis and evaluation of isatin analogs as caspase-3 inhibitors: Introduction of a hydrophilic group increases potency in a whole cell assay

Chu, Wenhua,Rothfuss, Justin,Zhou, Dong,MacH, Robert H.

supporting information; experimental part, p. 2192 - 2197 (2011/05/15)

A series of isatin analogs containing a hydrophilic group, including a pyridine ring, ethylene glycol group, and a triazole ring, have been synthesized, and their inhibition potency for caspase-3 was measured both in vitro (i.e., recombinant enzyme) and in whole cells (HeLa cells). The analogs having a hydrophilic group, including 12, 13, 16, 38, and 40, have dramatically increased activity in vitro and in HeLa cells compared to the corresponding unsubstituted N-phenyl isatin analogs.

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