4175-76-2

Basic information

• Product Name: 2,4-Dichlorothiazole
• Synonyms: 2,4-Dichlorothiazole ,98%;Thiazole, 2,4-dichloro-;2,4-DICHLORO-1,3-THIAZOLE;2,4-DICHLOROTHIAZOLE;2,4-DICHLOROTHIAZOLE,98.0+%(GC);2,4-Dichlorothiazole(WX636073)
• CAS NO: 4175-76-2
• Molecular Formula: C₃HCl₂NS
• Molecular Weight: 154.02
• Product Categories: Heterocyclic Compounds;Thiazoles
• Mol File: 4175-76-2.mol
• Article Data: 13

Chemical Properties

• Melting Point: 44 °C
• Boiling Point: 184 °C
• Flash Point: 90.999 °C
• Appearance: White to off-white crystalline powder
• Density: 1.603 g/cm³
• Vapor Pressure: 0.12mmHg at 25°C
• Refractive Index: 1.592
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: -1.93±0.10(Predicted)
• CAS DataBase Reference: 2,4-Dichlorothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dichlorothiazole(4175-76-2)
• EPA Substance Registry System: 2,4-Dichlorothiazole(4175-76-2)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• HazardClass: IRRITANT
• Hazardous Substances Data: 4175-76-2(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C3HCl2NS/c4-2-1-7-3(5)6-2/h1H

Upstream product

• 2295-31-0 thiazoline-2,4-dione 

Downstream Products

• 139670-00-1 4-chloro-2-(piperidin-1-yl)thiazole-5-carbaldehyde 
• 129880-84-8 4-chloro-2-(morpholin-4-yl)-thiazole-5-carbaldehyde 
• 125759-82-2 2,4-Dichloro-thiazole-5-carboxylic acid ethyl ester 
• 139669-91-3 (2,4-Dichloro-thiazol-5-yl)-phenyl-methanol 
• 139669-92-4 (2,4-Dichloro-thiazol-5-yl)-diphenyl-methanol 
• 62019-56-1 2,4-dichloro-thiazole-5-carboxylic acid 
• 92972-48-0 2,4-dichlorothiazole-5-carboxaldehyde 
• 129865-54-9 4-chloro-2-dimethylamino-1,3-thiazole-5-carbaldehyde 
• 848841-68-9 4-(4-chlorothiazol-2-yl)morpholine 
• 107190-42-1 2,4-dichloro-5-nitro-thiazole 
• 1258421-27-0 ethyl 2-(4-chloro-1,3-thiazol-2-yl)benzoate 

Relevant articles and documents

Dialkoxybithiazole: A new building block for head-to-head polymer semiconductors

Polymer semiconductors have received great attention for organic electronics due to the low fabrication cost offered by solution-based printing techniques. To enable the desired solubility/processability and carrier mobility, polymers are functionalized with hydrocarbon chains by strategically manipulating the alkylation patterns. Note that head-to-head (HH) linkages have traditionally been avoided because the induced backbone torsion leads to poor π-π overlap and amorphous film microstructures, and hence to low carrier mobilities. We report here the synthesis of a new building block for HH linkages, 4,4′-dialkoxy-5,5′-bithiazole (BTzOR), and its incorporation into polymers for high performance organic thin-film transistors. The small oxygen van der Waals radius and intramolecular S(thiazolyl) ?O(alkoxy) attraction promote HH macromolecular architectures with extensive π-conjugation, low bandgaps (1.40-1.63 eV), and high crystallinity. In comparison to previously reported 3,3′-dialkoxy-2,2′-bithiophene (BTOR), BTzOR is a promising building block in view of thiazole geometric and electronic properties: (a) replacing (thiophene)C-H with (thiazole)N reduces steric encumbrance in -BTzOR-Ar.06-0.25 cm2/(V s)) in organic thin-film transistors, as well as enhanced Ion:Ioff ratios and greater ambient stability than the BTOR analogues. These geometric and electronic properties make BTzOR a promising building block for new classes of polymer semiconductors, and the synthetic route to BTzOR reported here should be adaptable to many other bithiazole-based building blocks.

1-(DIHYDRONAPHTHALENYL)PYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

Provided are 1-(dihydronaphthalenyl)pyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy for the treatment of obesity and diabetes.

Novel insecticides

Compounds of formula I wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula I can be used as agrochemical active ingredients and can be prepared in a manner known per se.