417704-22-4

Basic information

• Product Name: 1,3-dihydro-4-isobenzo- furanol
• Synonyms: 1,3-dihydro-4-isobenzo- furanol
• CAS NO: 417704-22-4
• Molecular Weight: 136.15
• Mol File: 417704-22-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,3-dihydro-4-isobenzo- furanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dihydro-4-isobenzo- furanol(417704-22-4)
• EPA Substance Registry System: 1,3-dihydro-4-isobenzo- furanol(417704-22-4)

Safety Data

• Hazardous Substances Data: 417704-22-4(Hazardous Substances Data)

Usage

Family

Furan compounds

Physical state

Colorless liquid

Odor

Sweet, floral

Fragrance industry

Used as a fragrance ingredient

Food industry

Used as a flavoring agent, adding a sweet and aromatic note to various food and beverage products

Toxicity

Low toxicity

Safety

Considered safe for use in consumer products when used in appropriate concentrations

Handling

Should be handled with care and in accordance with safety guidelines

Upstream product

• 1402667-16-6 4-bromo-1,3-dihydroisobenzofuran 
• 127168-82-5 3-bromo-1,2-bis(bromomethyl)benzene 
• 576-23-8 2,3-dimethylbromobenzene 
• 892869-23-7 4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-1,3-dihydro-isobenzofuran 
• 533934-25-7 2-[5-(t-butyldimethylsilyl)]furylmethyl propargyl ether 
• 32904-79-3 2-((prop-2-yn-1-yloxy)methyl)furan 

Downstream Products

• 4792-33-0 4-methoxyphthalide 
• 1380696-10-5 (5R)-3-[4-(1,3-dihydro-2-benzofuran-4-yloxy)phenyl]-5-methyl-2,4-imidazolidinedione 
• 1380697-18-6 N₁-[4-(1,3-dihydro-2-benzofuran-4-yloxy)phenyl]-D-alaninamide 
• 1380697-17-5 1,1-dimethylethyl ((1R)-2-{[4-(1,3-dihydro-2-benzofuran-4-yloxy)phenyl]amino}-1-methyl-2-oxoethyl)carbamate 
• 1380697-15-3 4-(1,3-dihydro-2-benzofuran-4-yloxy)aniline 
• 1380697-13-1 4-[(4-nitrophenyl)oxy]-1,3-dihydro-2-benzofuran 

Relevant articles and documents

THIENODIAZEPINE DERIVATIVES AND APPLICATION THEREOF

The present invention relates to a class of thienodiazepine derivatives and an application thereof in the preparation of a drug for the treatment of diseases associated with bromodomain and extra-terminal (BET) Bromodomain inhibitors. Specifically, the present invention relates to compounds represented by formulas (I) and (II), as well as pharmaceutically acceptable salts thereof.

HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.

'Clicking' molecular hooks on silica nanoparticles to immobilize catalytically important metal complexes: The case of gold catalyst immobilization

Gold mediated reactions have emerged as one of the best choices for affecting a variety of chemical transformations with a wide range of functional group tolerance. Application of such transformations to industrial processes necessitates immobilization of the Au ions into a matrix for easy separation of the catalyst after reaction. We report the synthesis and characterization of silica nanoparticles in which Au(iii) has been immobilized through a 1,2,3-triazole linkage using an alkynalated picolinic acid exploiting "click chemistry". The Au(iii) immobilized silica nanoparticle has been thoroughly characterized using FT-IR, 13C CP MAS NMR and XPS. The utility of these particles as an easily separable catalyst for the Hashmi phenol synthesis is also reported.