4180-30-7

Basic information

• Product Name: Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)carbonyl]-
• CAS NO: 4180-30-7
• Molecular Formula: C11H22N4O
• Mol File: 4180-30-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)carbonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)carbonyl]-(4180-30-7)
• EPA Substance Registry System: Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)carbonyl]-(4180-30-7)

Safety Data

• Hazardous Substances Data: 4180-30-7(Hazardous Substances Data)

Usage

General Description

Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)carbonyl]- is a chemical compound with a molecular formula of C13H24N4O. It is commonly used as an antipsychotic medication and a potent dopamine antagonist. Piperazine, 1-methyl-4-[(4-methyl-1-piperazinyl)carbonyl]- acts on the central nervous system and is often used in the treatment of schizophrenia and other psychiatric disorders. It functions by blocking the transmission of neurotransmitters in the brain, leading to its therapeutic effects. Additionally, it may also have applications in the treatment of certain gastrointestinal disorders and as an antihistamine.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 75-44-5 phosgene 
• 56-23-5 tetrachloromethane 
• 201230-82-2 carbon monoxide 
• 39539-66-7 4-methyl-piperazine-1-carbonyl chloride 

Relevant articles and documents

Preparation method of substituted urea compound

The invention provides a preparation method of a substituted urea compound. The preparation method comprises the following steps: taking a nitrogen-containing heterocyclic compound and tetrahalomethane as raw materials, carrying out illumination catalytic reaction in the presence of a catalyst and a solvent to prepare the substituted urea compound and a halogen simple substance; the preparation method is wide in raw material source, phosgene, triphosgene and the like which are high in toxicity are prevented from being adopted as raw materials, the influence of the preparation process on the environment is reduced, and the atom utilization rate of the reaction is increased; the reaction conditions are mild, the operation is simple and convenient, the environmental pollution is reduced, and the reaction cost is reduced; the product yield is high, the halogen simple substance is co-produced, the additional value is high, a large amount of waste is prevented from being generated, and the method has high atom economy and environment friendliness and is beneficial to application and popularization.

Organic ligand and solvent free oxidative carbonylation of amine over Pd/TiO2 with unprecedented activity

A highly active Pd/TiO2 catalyst system was prepared and applied in the oxidative carbonylation of amines to ureas with ultra-low Pd content under organic ligand and solvent free conditions. The catalytic turnover frequencies (TOFs, moles of amines converted per mole of Pd per h) were 126000 and 250000 h-1 for the production of diphenylurea and dibenzylurea, respectively. An expanded substrate scope including the electron-rich and electron-deficient anilines, primary aliphatic amines, secondary amines was also established. This work offers a straightforward, step economic, and green methodology for the efficient synthesis of valuable ureas.

NOVEL PIPERIDINE DERIVATIVES AS HISTAMINE H3 RECEPTOR LIGANDS FOR TREATMENT OF DEPRESSION

Compounds of formula (I) wherein Ar1 and Q are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the treatme