41886-30-0 Usage
Description
(1E,3E)-(Phenylhydrazono)malonaldehyde dioxime is a chemical compound with the molecular formula C9H10N4O2. It is an organic compound that contains a phenylhydrazone functional group and two oxime groups. This versatile compound is known for its potential applications in both laboratory and industrial settings.
Uses
Used in Synthesis of Heterocyclic Compounds:
(1E,3E)-(Phenylhydrazono)malonaldehyde dioxime is used as a synthetic intermediate for the production of heterocyclic compounds, which are important in various chemical and pharmaceutical applications due to their unique properties and structures.
Used in Analytical Chemistry:
(1E,3E)-(Phenylhydrazono)malonaldehyde dioxime is used as a reagent for the determination of trace amounts of nickel. Its ability to form coordination complexes with metal ions makes it a valuable tool in analytical chemistry for detecting and quantifying specific metal ions.
Used in Biochemical Applications:
(1E,3E)-(Phenylhydrazono)malonaldehyde dioxime is used in biochemical applications for its potential to form coordination complexes with metal ions. This property allows it to be utilized in the study and manipulation of metal ion-dependent biological processes.
Used in Antimicrobial Applications:
(1E,3E)-(Phenylhydrazono)malonaldehyde dioxime has been studied for its potential antimicrobial properties. It may be used as an antimicrobial agent to combat various microorganisms, contributing to the development of new antimicrobial drugs or treatments.
Used in Antioxidant Applications:
(1E,3E)-(Phenylhydrazono)malonaldehyde dioxime has also been investigated for its antioxidant properties. It may be used as an antioxidant in various industrial applications, such as in the food and pharmaceutical industries, to prevent oxidation and extend the shelf life of products.
Check Digit Verification of cas no
The CAS Registry Mumber 41886-30-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,8,8 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 41886-30:
(7*4)+(6*1)+(5*8)+(4*8)+(3*6)+(2*3)+(1*0)=130
130 % 10 = 0
So 41886-30-0 is a valid CAS Registry Number.
41886-30-0Relevant articles and documents
Synthesis and structure-activity relationships of antitubercular 2-nitroimidazooxazines bearing heterocyclic side chains
Sutherland, Hamish S.,Blaser, Adrian,Kmentova, Iveta,Franzblau, Scott G.,Wan, Baojie,Wang, Yuehong,Ma, Zhenkun,Palmer, Brian D.,Denny, William A.,Thompson, Andrew M.
experimental part, p. 855 - 866 (2010/06/15)
Recently described biphenyl analogues of the antituberculosis drug PA-824 displayed improved potencies against M. tuberculosis but were poorly soluble. Heterobiaryl analogues of these, in which the first phenyl ring was replaced with various 5-membered ring heterocycles, were prepared with the aim of identifying potent new candidates with improved aqueous solubility. The compounds were constructed by coupling the chiral 2-nitroimidazooxazine alcohol with various halomethyl-substituted arylheterocycles, by cycloadditions to a propargyl ether derivative of this alcohol, or by Suzuki couplings on haloheterocyclic methyl ether derivatives. The arylheterocyclic compounds were all more hydrophilic than their corresponding biphenyl analogues, and several showed solubility improvements. 1-Methylpyrazole, 1,3-linked-pyrazole, 2,4-linked-triazole, and tetrazole analogues had 3- to 7-fold higher MIC potencies against replicating M. tb than predicted by their lipophilicities. Two pyrazole analogues were >10-fold more efficacious than the parent drug in a mouse model of acute M. tb infection, and one displayed a 2-fold higher solubility. 2009 American Chemical Society.
