41939-61-1

Basic information

• Product Name: N1-Methyl-4-nitro-o-phenyldiamin
• Synonyms: N1-Methyl-4-nitro-o-phenyldiamin;N~1~-methyl-4-nitro-1,2-benzenediamine;1-(Methylamino)-4-nitrobenzen-2-amine;N-Methyl-4-nitro-1,2-benzenediamine;N1-Methyl-4-nitrobenzene-1,2-diamine;1,2-benzenediamine, N~1~-methyl-4-nitro-;2-Methylamino-5-nitroaniline;N’-Methyl-4-nitrophenylene-1,2-diamine
• CAS NO: 41939-61-1
• Molecular Formula: C₇H₉N₃O₂
• Molecular Weight: 167.16526
• EINECS: 1308068-626-2
• Product Categories: API;Amines;Aromatics;amine | nitro-compound
• Mol File: 41939-61-1.mol
• Article Data: 20

Chemical Properties

• Melting Point: 174-176°
• Boiling Point: 366.8 °C at 760 mmHg
• Flash Point: 175.6 °C
• Appearance: Red powder
• Density: 1.359 g/cm³
• Vapor Pressure: 1.43E-05mmHg at 25°C
• Refractive Index: 1.682
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Ethyl Acetate (Slightly), Methanol (Slightly)
• PKA: 4.23±0.10(Predicted)
• CAS DataBase Reference: N1-Methyl-4-nitro-o-phenyldiamin(CAS DataBase Reference)
• NIST Chemistry Reference: N1-Methyl-4-nitro-o-phenyldiamin(41939-61-1)
• EPA Substance Registry System: N1-Methyl-4-nitro-o-phenyldiamin(41939-61-1)

Safety Data

• RIDADR: UN 2811 6.1/PG III
• HazardClass: IRRITANT
• PackingGroup: III
• Hazardous Substances Data: 41939-61-1(Hazardous Substances Data)

Usage

Description

N1-Methyl-4-nitro-o-phenyldiamin, also known as N'-Methyl-4-nitrophenylene-1,2-diamine, is an organic compound with the CAS number 41939-61-1. It is characterized by its red powder appearance and is utilized in various organic synthesis processes due to its unique chemical properties.

Uses

Used in Organic Synthesis:
N1-Methyl-4-nitro-o-phenyldiamin is used as a synthetic building block for the creation of various organic compounds. Its application in organic synthesis is attributed to its reactivity and ability to form a wide range of chemical products, making it a valuable component in the development of new materials and chemicals.
Used in Chemical Research:
In the field of chemical research, N1-Methyl-4-nitro-o-phenyldiamin serves as a key compound for studying the properties and behavior of similar organic compounds. Its use in research helps scientists understand the underlying mechanisms and interactions of related molecules, contributing to the advancement of chemical knowledge.
Used in Pharmaceutical Industry:
N1-Methyl-4-nitro-o-phenyldiamin is used as an intermediate in the synthesis of pharmaceutical compounds. Its application in the pharmaceutical industry is due to its potential role in the development of new drugs and therapeutic agents, as it can be modified and combined with other molecules to create novel medicinal compounds.
Used in Dye Manufacturing:
In the dye manufacturing industry, N1-Methyl-4-nitro-o-phenyldiamin is used as a starting material for the production of various dyes and pigments. Its red powder form and chemical properties make it suitable for the creation of colorants used in different applications, such as textiles, plastics, and printing inks.
Used in Analytical Chemistry:
N1-Methyl-4-nitro-o-phenyldiamin is employed as a reagent in analytical chemistry for the detection and quantification of specific substances. Its unique chemical properties allow it to react with certain compounds, enabling chemists to identify and measure their concentrations in various samples.

InChI:InChI=1/C7H9N3O2/c1-9-7-3-2-5(10(11)12)4-6(7)8/h2-4,9H,8H2,1H3

Upstream product

• 2044-88-4 N-methyl-2,4-dinitroaniline 
• 6283-25-6 H₂NC₆H₃(Cl)NO₂ 
• 74-89-5 methylamine 
• 369-36-8 6-fluoro-3-nitroaniline 
• 108-01-0 2-(N,N-dimethylamino)ethanol 
• 1313-82-2 sodium sulfide 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 593-51-1 methylamine hydrochloride 

Downstream Products

• 53987-29-4 acetic acid-(2-methylamino-5-nitro-anilide) 
• 70894-12-1 5-amino-2-(4-aminophenyl)-1-methylbenzimidazole 
• 106167-15-1 1-methyl-5-nitro-2-(4-nitrophenyl)-1H-benzo[d]imidazole 
• 10205-95-5 N,N-diethyl-4-(1-methyl-5-nitro-1H-benzoimidazol-2-yl)-aniline 
• 10205-94-4 N,N-dimethyl-4-(1-methyl-5-nitro-1H-benzoimidazol-2-yl)-aniline 
• 7466-45-7 6-nitro-2,3-diphenylquinoxaline 
• 66108-85-8 1-methyl-5-nitro-1,3-dihydro-2H-benzo[d]imidazol-2-one 
• 108718-77-0 1-methyl-2-(4-methyl-3-nitro-phenyl)-5-nitro-1H-benzimidazole 
• 25877-34-3 1-methyl-5-nitro-1H-benzo[d][1,2,3]triazole 
• 41939-48-4 1-methyl-5-nitro-2-(5-phenyl-furan-2-yl)-1H-benzoimidazole 
• 41939-51-9 2-[5-(4-chloro-phenyl)-furan-2-yl]-1-methyl-5-nitro-1H-benzoimidazole 
• 41939-50-8 2-[5-(4-methoxy-phenyl)-furan-2-yl]-1-methyl-5-nitro-1H-benzoimidazole 
• 41939-53-1 1-methyl-5-nitro-2-[5-(4-nitro-phenyl)-furan-2-yl]-1H-benzoimidazole 
• 41939-49-5 1-methyl-5-nitro-2-(5-p-tolyl-furan-2-yl)-1H-benzoimidazole 

Relevant articles and documents

Flavin mimetics: Synthesis and photophysical properties

We report the synthesis of new isoalloxazines using a microwave-assisted approach to make N-substituted-2-nitroanilines followed by one-pot reduction and condensation via Hemmerich's method. The influence of substituents on positions 7, 8, and 10 of flavin core on the optical properties is investigated. The aliphatic functionalities on N10 give rise to quantum yields of 0.7, while aromatic side-chains quench fluorescence. Relaxed geometries (DFT) of chiral and achiral derivatives have been used for TD-DFT calculations, which yielded good agreement with the experimental UV and CD data.

2-(4-ARYL-1H-IMIDAZOL-1-YL)ANILINE COMPOUNDS

The present invention provides compounds that are useful as vaccine adjuvants and/or antitumor agents and methods for producing and using the same. In one particular aspect of the invention, compounds of the invention are of the formula (I) where R1, R2, R3 and Ar1 are those defined herein.

COMPOUNDS FOR USE IN INHIBITING HIV CAPSID ASSEMBLY

The present invention relates to a compound or a pharmaceutically acceptable salt or solvate thereof for use in inhibiting HIV capsid assembly, the compound comprising the core structure wherein E is CR7or S, and wherein f is 0 or 1, and wherein in case E is S, f is 0, and wherein the core structure is at least substituted in 2 and 4 position, and wherein the residue R6 and R7, are, independently of each other, selected from the group consisting of -H, -D, -alkyl, alkoxy, alkenyl, alkynyl, halides, -NO2, - OH, -NH2, -NHR4#, -CN, - S(O)R4#, -SO2R4#, -P(O)R4#R5#, -P(O)(OR4#)R5#, -P(O)(OR4#)(OR5#), -C(O)NR4#R5#, - C(O)SR4#, -C(O)R4#, -C(O)O-R4#, alkoxy and glycol chains; and wherein R6 may optionally form a cyclic residue, with a further substituent present 5 or 6 position, and wherein R4# and R5# are, independently of each other, selected from the group consisting of -H, -alkyl, -alkenyl, -heterocyclo alkyl, aryl and heteroaryl.