41995-19-1

Basic information

• Product Name: 2-(3,4-DICHLOROPHENYL)-2-OXOETHYLAMINE HYDROCHLORIDE
• Synonyms: 2-(3,4-DICHLOROPHENYL)-2-OXOETHYLAMINE HYDROCHLORIDE;2-Amino-1-(3,4-dichlorophenyl)ethanone hydrochloride;2-aMino-1-(3,4-dichlorophenyl)ethan-1-one hydrochloride
• CAS NO: 41995-19-1
• Molecular Formula: C₈H₇Cl₂NO*ClH
• Molecular Weight: 240.51
• Mol File: 41995-19-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 371.9 °C at 760 mmHg
• Flash Point: 178.7 °C
• Appearance: /
• Vapor Pressure: 6.83E-06mmHg at 25°C
• CAS DataBase Reference: 2-(3,4-DICHLOROPHENYL)-2-OXOETHYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-DICHLOROPHENYL)-2-OXOETHYLAMINE HYDROCHLORIDE(41995-19-1)
• EPA Substance Registry System: 2-(3,4-DICHLOROPHENYL)-2-OXOETHYLAMINE HYDROCHLORIDE(41995-19-1)

Safety Data

• Hazardous Substances Data: 41995-19-1(Hazardous Substances Data)

Usage

General Description

2-(3,4-Dichlorophenyl)-2-oxoethylamine hydrochloride is a chemical compound that consists of a phenyl ring with two chlorine atoms, an ethylamine group, and a ketone group, all attached to a central carbon atom. 2-(3,4-Dichlorophenyl)-2-oxoethylamine hydrochloride is commonly used in pharmaceutical research for the synthesis of potential drugs and medications. As a hydrochloride salt, it is more stable and water-soluble, making it easier to handle and administer in research and clinical settings. The compound's properties and structure make it a valuable building block in the development of new chemical entities and drug candidates. Furthermore, it has potential applications in the treatment of various diseases and disorders, including neurological and psychiatric conditions.

InChI:InChI=1/C8H7Cl2NO.ClH/c9-6-2-1-5(3-7(6)10)8(12)4-11;/h1-3H,4,11H2;1H

Upstream product

• 318949-24-5 (3,4-dichloro-phenacyl)-hexamethylenetetraminium; bromide 
• 875306-52-8 C₁₀H₇Cl₂NO₃ 
• 380650-10-2 2-amino-1-(3,4-dichloro-phenyl)-ethanone 
• 2632-10-2 2-bromo-1-(3,4-dichlorophenyl)ethanone 
• 2642-63-9 3',4'-dichloroacetophenone 

Downstream Products

• 64748-91-0 N-[2-(3,4-dichloro-phenyl)-2-oxo-ethyl]-2-(2,4-dioxo-imidazolidin-1-ylimino)-acetamide 
• 663181-08-6 C₁₄H₁₀Cl₂N₂O₂ 
• 3567-82-6 2-amino-1-(3,4-dichlorophenyl)ethan-1-ol 
• 1254941-84-8 2-(3-([1,2,4]triazolo[1,5-a;]pyridin-6-yl)benzylamino)-1-(3,4-dichlorophenyl)ethanol 
• 1190234-79-7 ethyl 1-(2-{[2-(3,4-dichlorophenyl)-2-oxoethyl]amino}-2-oxoethyl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate 

Relevant articles and documents

NOVEL ARYL-CYANOGUANIDINE COMPOUNDS

The present invention relates to protein-lysine N-methyltransferase SMYD2 (SET and MYND domain-containing protein 2) inhibitors, in particular SMYD2-inhibitory substituted cyanoguanidine-pyrazolines of general formula (I) wherein R1, R2/s

NOVEL ARYL-CYANOGUANIDINE COMPOUNDS

The present invention relates to protein-lysine N-methyltransferase SMYD2 (SET and MYND domain-containing protein 2) inhibitors, in particular SMYD2-inhibitory substituted cyanoguanidine- pyrazolines of general formula (I), wherein R1, R2, R3, R4 and R5 have the meaning as described and defined herein, as well as to pharmaceutical compositions comprising compounds according to the invention and to their prophylactic and therapeutic use for hyperproliferative disorders, in particular for cancer, respectively tumour disorders. The present invention furthermore relates to the use of SMYD2 inhibitors for benign hyperplasias, atherosclerotic disorders, sepsis, autoimmune disorders, vascular disorders, viral infections, neurodegenerative disorders, inflammatory disorders, atherosclerotic disorders and the control of male fertility.

ARYL, HETEROARYL, AND HETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF

Novel aryl, heteroaryl, and non-aromatic heterocyle substituted tetrahydroisoquinolines are described in the present invention. These compounds are used in the treatment of various neurological and physiological disorders. Methods of making these compounds are also described in the present invention.