41996-97-8Relevant articles and documents
Monomers containing substrate or inhibitor residues for copper amine oxidases and their hydrophilic beaded resins designed for enzyme interaction studies
Bertini, Vincenzo,Alfei, Silvana,Pocci, Marco,Lucchesini, Francesco,Picci, Nevio,Iemma, Francesca
, p. 11407 - 11414 (2004)
Five styrenic monomers, four with aminoalkyl residues typical of copper containing amine oxidase substrates and one with a 2,6-dialkoxybenzylamine residue which mimics previously prepared selective substrate-like benzylamine oxidase inhibitors, have been synthesized and transformed into radical homopolymers, copolymers with N,N-dimethylacrylamide (DMAA), and hydrophilic beaded resins, designed for enzyme interaction studies aimed in finding new materials for highly biospecific chromatographic separations. The five monomers have given beaded resins of 125-500 μm swellable in water with a volume increase of 1200-1500%. The four aminoalkyl monomers have given water soluble copolymers some of which are good substrates of benzylamine oxidase (BAO), diamine oxidase (DAO) and lysyl oxidase (LO), up to 9.7 times better than elastin for LO. Graphical Abstract.
Crossed aldol reaction using cross-linked polymer-bound lithium dialkylamide
Seki, Atsushi,Ishiwata, Fusae,Takizawa, Youichi,Asami, Masatoshi
, p. 5001 - 5011 (2007/10/03)
Cross-linked polymer-bound lithium dialkylamides were employed in crossed aldol reaction of various carbonyl compounds with aldehydes to afford the corresponding β-hydroxycarbonyl compounds. The introduction of spacer chains to the polymer-bound lithium d