42013-66-1Relevant articles and documents
Dezocine production process
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Paragraph 0045; 0059; 0061, (2019/10/10)
The invention provides a dezocine production process, and relates to the technical field of medical chemistry. The dezocine production process comprises the following steps of 1) synthesis of dezocine ammonium salt, 2) synthesis of methyl dezocine salt, 3) synthesis of a crude dizocine product and 4) refining and packaging of the crude dizocine product. By means of the four processes of synthesis of dezocine ammonium salt, synthesis of methyl dezocine salt, synthesis of the crude dizocine product and refining and packaging of the crude dizocine product, the synthesis steps and the reaction conditions are optimized, the synthesis cycle is shortened, and meanwhile the detailed processes of the synthesis of dezocine ammonium salt, synthesis of methyl dezocine salt, synthesis of the crude dizocine product and refining of the crude dizocine product are described in details; key process parameters and product quality standards are defined, thus the dezocine production process can rapidly grasp key control points, and the synthesis reaction can be helped to be conducted efficiently and stably.
