42063-01-4Relevant articles and documents
RhIII-Catalyzed Synthesis of Highly Substituted 2-Pyridones using Fluorinated Diazomalonate
Das, Debapratim,Sahoo, Gopal,Biswas, Aniruddha,Samanta, Rajarshi
supporting information, p. 360 - 364 (2020/01/25)
A RhIII-catalyzed strategy was developed for the rapid construction of highly substituted 2-pyridone scaffolds using α,β-unsaturated oximes and fluorinated diazomalonate. The reaction proceeds through direct, site-selective alkylation based on migratory insertion and subsequent cyclocondensation. A wide substrate scope with different functional groups was explored. The requirement of fluorinated diazomalonate was explored for this transformation. The developed methodology was further extended with the synthesis of the bioactive compound.
Synthesis of certain unsubstituted, 9-exo-(dialkylaminomethyl)-, and 9- endo-(aralkyl)-tricyclo [5.2.1.02,6 decane-8-ketoxime esters and ethers with local anesthetic and analgesic activities
Aboul-Enein M, Nabil,El-Azzouny, Aida,Abdallah, Nevine A.,Maklad, Yousreya A.,Saleh, Ola A.,Ebeid
, p. 197 - 208 (2007/10/03)
The synthesis of series of unsubstituted, 9-exo-(dialkylaminomethyl)-, and 9-endo-(aralkyl)tricyclo [5.2.1.0(2,6)] decane-8-ketoximes esters and ethers 3a-j, 4a-d, 7a-j and 13a-d from the oxime synthons 2, 6a-e, 12a and 12b, respectively, is described. Al
Reactions with (Arylmethylene)cycloalkanones. 5. Synthesis of 2-Acetyl-5-aryl-5,6,7,8,9,10-hexahydrocycloheptathiazolopyrimidin-3(2H)-ones of Probable Biological Activity
All, Mohamed I.,Hammam, Abou El-Fotooh G.
, p. 342 - 343 (2007/10/02)
Cycloheptapyrimidine-2-thiones (III) were prepared by heating 2-(arylmethylene)cycloheptanones with thiourea in ethanolic potassium hydroxide.Compounds III reacted with chloroacetic acid in acetic anhydride to yield the title compounds (IV).Compounds I