42074-16-8

Basic information

• Product Name: N-BENZYL-N-(2-CHLOROETHYL)AMINE
• Synonyms: N-BENZYL-N-(2-CHLOROETHYL)AMINE;N-(2-Chloroethyl)benzylamine, Benzyl(2-chloroethyl)amine;N-Benzyl-2-chloroethylamine;N-Benzyl-2-chloroethan-1-amine
• CAS NO: 42074-16-8
• Molecular Formula: C₉H₁₂ClN
• Molecular Weight: 169.65
• Product Categories: Aminomethyl's;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 42074-16-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 245.1 °C at 760 mmHg
• Flash Point: 102.1 °C
• Appearance: /
• Density: 1.067 g/cm³
• PKA: 7.77±0.19(Predicted)
• CAS DataBase Reference: N-BENZYL-N-(2-CHLOROETHYL)AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZYL-N-(2-CHLOROETHYL)AMINE(42074-16-8)
• EPA Substance Registry System: N-BENZYL-N-(2-CHLOROETHYL)AMINE(42074-16-8)

Safety Data

• Hazardous Substances Data: 42074-16-8(Hazardous Substances Data)

Usage

General Description

N-Benzyl-N-(2-chloroethyl)amine is a chemical compound that belongs to the class of organic compounds known as benzylamines. It is a clear, colorless to slightly yellow liquid with a strong, amine-like odor. N-BENZYL-N-(2-CHLOROETHYL)AMINE is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is a versatile building block in organic chemistry and is widely used in the manufacturing of various chemicals and materials. N-Benzyl-N-(2-chloroethyl)amine is also known to be a skin and eye irritant and should be handled with care.

Upstream product

• 2510-33-0 N-benzyl-2-oxazolidinone 
• 100-46-9 benzylamine 
• 107-07-3 2-chloro-ethanol 
• 104-63-2 N-Benzylethanolamine 
• 2564-06-9 N-benzyl-2-chloroacetamide 
• 870-24-6 2-chloroethanamine hydrochloride 
• 100-52-7 benzaldehyde 

Downstream Products

• 82462-01-9 N¹-benzyl-N²-decylethane-1,2-diamine 
• 263719-86-4 N²-BOC-N⁵-benzyl-1,2,5-thiadiazolidine 1,1-dioxide 
• 1158255-34-5 N-(phenylmethyl)-1H-pyrrole-1-ethanamine 

Relevant articles and documents

Preparation method of chiral morpholine compound

The invention provides a preparation method of a chiral morpholine compound. With chiral ethylene oxide as a raw material, the preparation method comprises the steps of ring opening, cyclization and deprotection reaction to obtain the chiral 2-substituted morpholine compound. The preparation process is simple and environmentally friendly, has mild reaction conditions, is free of irritation or allergens, has higher total yield and good safety and is suitable for industrial amplification.

Sodium borohydride-boron trifluoride ethereate, a convenient and efficient reagent for the reduction of amides

Sodium borohydride-boron trifluoride ethereate has been employed as a reducing agent for the conversion of amides into amines, the reducing species being diborane generated in situ.This method successfully reduces primary, secondary and tertiary amides, lactams and chiral diketopiperazines, in moderate to high yields.An unusual ring cleavage is observed in the reduction of the pyrroloquinazolin-1-one (7a) resulting in the formation of benz-1,6-diazonine (7b).